STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
V4ALN5_LOTGIPyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (388 aa)    
Predicted Functional Partners:
V4A6K4_LOTGI
Dihydrolipoyl dehydrogenase.
 
 
 0.999
V4AQJ3_LOTGI
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 
 0.999
V4B766_LOTGI
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.999
V4BVZ4_LOTGI
Transket_pyr domain-containing protein.
 
 0.993
V4AKR5_LOTGI
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
  
 
 0.958
V4BQ42_LOTGI
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.955
V4ACD7_LOTGI
Pyruvate kinase; Belongs to the pyruvate kinase family.
   
 0.954
V4AYD4_LOTGI
Pyruvate kinase; Belongs to the pyruvate kinase family.
   
 0.954
V4CQH5_LOTGI
Uncharacterized protein.
  
 0.947
V3ZDP7_LOTGI
Malic enzyme.
  
 0.933
Your Current Organism:
Lottia gigantea
NCBI taxonomy Id: 225164
Other names: L. gigantea, owl limpet
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