node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
dxs | thiE | swp_3619 | swp_2331 | Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | Phosphomethylpyrimidine kinase/thiamin-phosphate pyrophosphorylase, putative; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.463 |
dxs | thiG | swp_3619 | swp_2335 | Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | Thiazole biosynthesis; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.925 |
dxs | thiI | swp_3619 | swp_3614 | Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | Thiamine biosynthesis protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.465 |
swp_0165 | swp_2334 | swp_0165 | swp_2334 | Molybdopterin biosynthesis MoeB protein. | ThiS, thiamine-biosynthesis. | 0.927 |
swp_0165 | swp_2336 | swp_0165 | swp_2336 | Molybdopterin biosynthesis MoeB protein. | ThiH protein. | 0.683 |
swp_0165 | swp_4909 | swp_0165 | swp_4909 | Molybdopterin biosynthesis MoeB protein. | Conserved hypothetical protein. | 0.595 |
swp_0165 | swp_5006 | swp_0165 | swp_5006 | Molybdopterin biosynthesis MoeB protein. | Molybdenum cofactor biosynthesis protein D. | 0.992 |
swp_0165 | thiC | swp_0165 | swp_2330 | Molybdopterin biosynthesis MoeB protein. | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.785 |
swp_0165 | thiE | swp_0165 | swp_2331 | Molybdopterin biosynthesis MoeB protein. | Phosphomethylpyrimidine kinase/thiamin-phosphate pyrophosphorylase, putative; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.941 |
swp_0165 | thiG | swp_0165 | swp_2335 | Molybdopterin biosynthesis MoeB protein. | Thiazole biosynthesis; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.923 |
swp_0165 | thiI | swp_0165 | swp_3614 | Molybdopterin biosynthesis MoeB protein. | Thiamine biosynthesis protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.419 |
swp_2332 | swp_2334 | swp_2332 | swp_2334 | ThiF protein, putative. | ThiS, thiamine-biosynthesis. | 0.998 |
swp_2332 | swp_2336 | swp_2332 | swp_2336 | ThiF protein, putative. | ThiH protein. | 0.905 |
swp_2332 | swp_4909 | swp_2332 | swp_4909 | ThiF protein, putative. | Conserved hypothetical protein. | 0.595 |
swp_2332 | swp_5006 | swp_2332 | swp_5006 | ThiF protein, putative. | Molybdenum cofactor biosynthesis protein D. | 0.863 |
swp_2332 | thiC | swp_2332 | swp_2330 | ThiF protein, putative. | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.951 |
swp_2332 | thiE | swp_2332 | swp_2331 | ThiF protein, putative. | Phosphomethylpyrimidine kinase/thiamin-phosphate pyrophosphorylase, putative; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.986 |
swp_2332 | thiG | swp_2332 | swp_2335 | ThiF protein, putative. | Thiazole biosynthesis; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.981 |
swp_2332 | thiI | swp_2332 | swp_3614 | ThiF protein, putative. | Thiamine biosynthesis protein; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. | 0.939 |
swp_2334 | swp_0165 | swp_2334 | swp_0165 | ThiS, thiamine-biosynthesis. | Molybdopterin biosynthesis MoeB protein. | 0.927 |