node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HP15_1362 | HP15_1851 | HP15_1362 | HP15_1851 | Chorismate mutase / prephenate dehydratase. | Para-aminobenzoate synthase, subunit I. | 0.900 |
HP15_1362 | aroA | HP15_1362 | HP15_1364 | Chorismate mutase / prephenate dehydratase. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.999 |
HP15_1362 | pabA | HP15_1362 | HP15_3289 | Chorismate mutase / prephenate dehydratase. | Para-aminobenzoate/anthranilate synthase glutamine amidotransferase component II. | 0.963 |
HP15_1362 | trpA | HP15_1362 | HP15_1826 | Chorismate mutase / prephenate dehydratase. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.666 |
HP15_1362 | trpB | HP15_1362 | HP15_1827 | Chorismate mutase / prephenate dehydratase. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.622 |
HP15_1362 | trpC | HP15_1362 | HP15_3291 | Chorismate mutase / prephenate dehydratase. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.673 |
HP15_1362 | trpD | HP15_1362 | HP15_3290 | Chorismate mutase / prephenate dehydratase. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.686 |
HP15_1362 | trpE | HP15_1362 | HP15_3288 | Chorismate mutase / prephenate dehydratase. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.961 |
HP15_1362 | trpF | HP15_1362 | HP15_1828 | Chorismate mutase / prephenate dehydratase. | Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. | 0.723 |
HP15_1851 | HP15_1362 | HP15_1851 | HP15_1362 | Para-aminobenzoate synthase, subunit I. | Chorismate mutase / prephenate dehydratase. | 0.900 |
HP15_1851 | aroA | HP15_1851 | HP15_1364 | Para-aminobenzoate synthase, subunit I. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.599 |
HP15_1851 | pabA | HP15_1851 | HP15_3289 | Para-aminobenzoate synthase, subunit I. | Para-aminobenzoate/anthranilate synthase glutamine amidotransferase component II. | 0.999 |
HP15_1851 | trpA | HP15_1851 | HP15_1826 | Para-aminobenzoate synthase, subunit I. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.942 |
HP15_1851 | trpB | HP15_1851 | HP15_1827 | Para-aminobenzoate synthase, subunit I. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.956 |
HP15_1851 | trpC | HP15_1851 | HP15_3291 | Para-aminobenzoate synthase, subunit I. | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.990 |
HP15_1851 | trpD | HP15_1851 | HP15_3290 | Para-aminobenzoate synthase, subunit I. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.990 |
HP15_1851 | trpE | HP15_1851 | HP15_3288 | Para-aminobenzoate synthase, subunit I. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.845 |
HP15_1851 | trpF | HP15_1851 | HP15_1828 | Para-aminobenzoate synthase, subunit I. | Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. | 0.952 |
aroA | HP15_1362 | HP15_1364 | HP15_1362 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Chorismate mutase / prephenate dehydratase. | 0.999 |
aroA | HP15_1851 | HP15_1364 | HP15_1851 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Para-aminobenzoate synthase, subunit I. | 0.599 |