node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ddl | ftsI | HP15_566 | HP15_558 | D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | 0.930 |
ddl | ftsL | HP15_566 | HP15_557 | D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Cell division protein, FtsL-like protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.826 |
ddl | ftsQ | HP15_566 | HP15_567 | D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Polypeptide-transport-associated domain protein, FtsQ-type; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.980 |
ddl | ftsW | HP15_566 | HP15_563 | D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Cell division protein FtsW-like protein; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.968 |
ddl | mrdA | HP15_566 | HP15_605 | D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Peptidoglycan glycosyltransferase; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.572 |
ddl | mrdB | HP15_566 | HP15_606 | D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | Rod shape-determining protein RodA-like protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.660 |
ddl | murC | HP15_566 | HP15_565 | D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramate-L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.998 |
ddl | murD | HP15_566 | HP15_562 | D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.986 |
ddl | murE | HP15_566 | HP15_559 | D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.958 |
ddl | murF | HP15_566 | HP15_560 | D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.998 |
ftsI | ddl | HP15_558 | HP15_566 | Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | D-alanine-D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. | 0.930 |
ftsI | ftsL | HP15_558 | HP15_557 | Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | Cell division protein, FtsL-like protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.965 |
ftsI | ftsQ | HP15_558 | HP15_567 | Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | Polypeptide-transport-associated domain protein, FtsQ-type; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.971 |
ftsI | ftsW | HP15_558 | HP15_563 | Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | Cell division protein FtsW-like protein; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.990 |
ftsI | mrdA | HP15_558 | HP15_605 | Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | Peptidoglycan glycosyltransferase; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.940 |
ftsI | mrdB | HP15_558 | HP15_606 | Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | Rod shape-determining protein RodA-like protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.956 |
ftsI | murC | HP15_558 | HP15_565 | Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | UDP-N-acetylmuramate-L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.951 |
ftsI | murD | HP15_558 | HP15_562 | Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | UDP-N-acetylmuramoylalanine-D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.926 |
ftsI | murE | HP15_558 | HP15_559 | Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.987 |
ftsI | murF | HP15_558 | HP15_560 | Penicillin-binding protein 3; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate-D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.951 |