STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EF_0799Autolysin; Hydrolyzes the cell wall of E.faecalis and M.lysodeikticus. May play an important role in cell wall growth and cell separation. (737 aa)    
Predicted Functional Partners:
ply-2
Endolysin; Similar to SP:Q06774, and PID:2347010; identified by sequence similarity; putative.
     
 0.717
EF_0798
Hypothetical protein; Identified by Glimmer2; putative.
 
   
 0.638
gelE
Coccolysin; Metalloprotease capable of the hydrolysis of insoluble hydrophobic substrates. Hydrolyzes azocoll and gelatin and, at a lower rate, soluble and insoluble collagens. Does not cleave short synthetic peptides. Preferentially hydrolyzes the 24-Phe-|-Phe-25 bond in the insulin B-chain, followed by the 5-His-|-Leu-6 bond. Inactivates endothelin-1, primarily by cleavage of the 5-Ser-|-Leu-6 and 16-His-|- Leu-17 bonds. Hydrolyzes the alpha chain of C3 to generate a C3b-like protein. Inhibits complement-mediated hemolysis and opsinization of bacteria. Hydrolyzes the insect antimicro [...]
  
 
 
 0.613
EF_0796
Type 2 phosphatidic acid phosphatase family protein; Similar to SP:Q05384, and PID:581543; identified by sequence similarity; putative.
  
  
 0.588
EF_0797
Conserved domain protein.
     
 0.565
ply-1
Endolysin; Similar to SP:Q38653, SP:Q06774, and PID:2347010; identified by sequence similarity; putative.
 
   
 0.544
EF_1817
Serine proteinase, V8 family; Similar to GB:Z11559, GB:M58510, SP:P21399, PID:33963, PID:896473, GB:Z11559, GB:M58510, SP:P21399, PID:33963, and PID:896473; identified by sequence similarity; putative; Belongs to the peptidase S1B family.
   
 
 0.530
EF_1823
N-acetylmuramoyl-L-alanine amidase, family 4; Similar to GB:X14487, SP:P13645, PID:28317, and PID:623409; identified by sequence similarity; putative.
 
  
0.520
EF_2318
Peptidase, M23/M37 family; Similar to GP:8100664; identified by sequence similarity; putative.
  
  
 0.488
EF_2373
Conserved hypothetical protein; Similar to GP:10174311; identified by sequence similarity; putative.
  
     0.484
Your Current Organism:
Enterococcus faecalis V583
NCBI taxonomy Id: 226185
Other names: E. faecalis V583, Enterococcus faecalis str. V583, Enterococcus faecalis strain V583
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