STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfk6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (320 aa)    
Predicted Functional Partners:
pyk
Pyruvate kinase; Identified by match to PFAM protein family HMM PF02629; Belongs to the pyruvate kinase family.
 
 
 0.994
pgi
Glucose-6-phosphate isomerase; Similar to GP:4928281, SP:P80860, and SP:P80860; identified by sequence similarity; putative.
  
 0.991
fba
Fructose-bisphosphate aldolase class-II; Similar to SP:O65944; identified by sequence similarity; putative.
 
 
 0.972
manA
Mannose-6-phosphate isomerase, class I; Identified by match to PFAM protein family HMM PF01238; Belongs to the mannose-6-phosphate isomerase type 1 family.
    
 0.936
lacB
Galactose-6-phosphate isomerase, LacB subunit; Similar to GB:X70326, SP:P49006, and PID:38435; identified by sequence similarity; putative.
 
 
 0.932
lacA
Galactose-6-phosphate isomerase, LacA subunit; Identified by match to TIGR protein family HMM TIGR01119.
 
 
 0.932
fbp
Fructose-1,6-bisphosphatase, putative.
     
 0.929
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
   
  
 0.921
mtlD
Mannitol-1-phosphate 5-dehydrogenase; Similar to PIR:C39435; identified by sequence similarity; putative; Belongs to the mannitol dehydrogenase family.
    
 0.921
cscK
Fructokinase; Identified by match to PFAM protein family HMM PF00480.
    
 0.918
Your Current Organism:
Enterococcus faecalis V583
NCBI taxonomy Id: 226185
Other names: E. faecalis V583, Enterococcus faecalis str. V583, Enterococcus faecalis strain V583
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.