STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ebsBEbsB protein; Seems to play some role in the cell surface expression of a chromosomally encoded receptor, named enterococcal binding substance (EBS), that mediates mating aggregate formation. Might interfere with the synthesis or assembly of EBS and function as a cell wall hydrolase. (135 aa)    
Predicted Functional Partners:
ebsa
ebsA protein; Seems to play some role in the cell surface expression of a chromosomally encoded receptor, named enterococcal binding substance (EBS), that mediates mating aggregate formation. Might interfere with the synthesis or assembly of EBS, and/or assist in the localization of EbsB to the cell wall; Belongs to the EbsA family.
     
 0.967
comG6
Competence protein; Similar to GP:3287181, and GP:3287181; identified by sequence similarity; putative.
      
 0.700
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
 
 
 0.692
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
   
 
 0.675
topB-1
DNA topoisomerase III; Similar to SP:P33446, GB:X64876, PID:313842, SP:P33446, GB:X64876, and PID:313842; identified by sequence similarity; putative.
   
 
 0.652
EF_1381
Conserved hypothetical protein TIGR00486; Similar to SP:P54472, GB:L34355, GB:L34355, GB:L35853, GB:L46810, GB:U08895, PID:511587, PID:533184, PID:557731, and PID:950329; identified by sequence similarity; putative; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
  
  
 0.610
EF_2813
Tail tape meausure protein; Similar to GP:8918797; identified by sequence similarity; putative.
      
 0.584
EF_2341
Hypothetical protein; Identified by Glimmer2; putative.
  
  
 0.556
ssb-1
Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
   
 
 0.555
ssb-2
Single-strand binding protein; Similar to GP:5001700, and GP:9789553; identified by sequence similarity; putative.
   
 
 0.555
Your Current Organism:
Enterococcus faecalis V583
NCBI taxonomy Id: 226185
Other names: E. faecalis V583, Enterococcus faecalis str. V583, Enterococcus faecalis strain V583
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.