node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
purC | purD | EF_1785 | EF_1777 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Similar to SP:P12046; identified by sequence similarity; putative; Belongs to the SAICAR synthetase family. | Phosphoribosylamine--glycine ligase; Similar to SP:P12039; identified by sequence similarity; putative; Belongs to the GARS family. | 0.996 |
purC | purE | EF_1785 | EF_1787 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Similar to SP:P12046; identified by sequence similarity; putative; Belongs to the SAICAR synthetase family. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.998 |
purC | purF | EF_1785 | EF_1781 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Similar to SP:P12046; identified by sequence similarity; putative; Belongs to the SAICAR synthetase family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.996 |
purC | purH | EF_1785 | EF_1778 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Similar to SP:P12046; identified by sequence similarity; putative; Belongs to the SAICAR synthetase family. | Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Similar to SP:P12048; identified by sequence similarity; putative. | 0.996 |
purC | purK-1 | EF_1785 | EF_1786 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Similar to SP:P12046; identified by sequence similarity; putative; Belongs to the SAICAR synthetase family. | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.927 |
purC | purL | EF_1785 | EF_1782 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Similar to SP:P12046; identified by sequence similarity; putative; Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.990 |
purC | purM | EF_1785 | EF_1780 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Similar to SP:P12046; identified by sequence similarity; putative; Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamidine cyclo-ligase; Similar to SP:P12043; identified by sequence similarity; putative. | 0.996 |
purC | purN | EF_1785 | EF_1779 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Similar to SP:P12046; identified by sequence similarity; putative; Belongs to the SAICAR synthetase family. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.992 |
purC | purQ | EF_1785 | EF_1783 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Similar to SP:P12046; identified by sequence similarity; putative; Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamidine synthetase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.989 |
purC | purS | EF_1785 | EF_1784 | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Similar to SP:P12046; identified by sequence similarity; putative; Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamidine synthase, PurS protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] | 0.986 |
purD | purC | EF_1777 | EF_1785 | Phosphoribosylamine--glycine ligase; Similar to SP:P12039; identified by sequence similarity; putative; Belongs to the GARS family. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Similar to SP:P12046; identified by sequence similarity; putative; Belongs to the SAICAR synthetase family. | 0.996 |
purD | purE | EF_1777 | EF_1787 | Phosphoribosylamine--glycine ligase; Similar to SP:P12039; identified by sequence similarity; putative; Belongs to the GARS family. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.998 |
purD | purF | EF_1777 | EF_1781 | Phosphoribosylamine--glycine ligase; Similar to SP:P12039; identified by sequence similarity; putative; Belongs to the GARS family. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.999 |
purD | purH | EF_1777 | EF_1778 | Phosphoribosylamine--glycine ligase; Similar to SP:P12039; identified by sequence similarity; putative; Belongs to the GARS family. | Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Similar to SP:P12048; identified by sequence similarity; putative. | 0.998 |
purD | purK-1 | EF_1777 | EF_1786 | Phosphoribosylamine--glycine ligase; Similar to SP:P12039; identified by sequence similarity; putative; Belongs to the GARS family. | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.957 |
purD | purL | EF_1777 | EF_1782 | Phosphoribosylamine--glycine ligase; Similar to SP:P12039; identified by sequence similarity; putative; Belongs to the GARS family. | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.994 |
purD | purM | EF_1777 | EF_1780 | Phosphoribosylamine--glycine ligase; Similar to SP:P12039; identified by sequence similarity; putative; Belongs to the GARS family. | Phosphoribosylformylglycinamidine cyclo-ligase; Similar to SP:P12043; identified by sequence similarity; putative. | 0.999 |
purD | purN | EF_1777 | EF_1779 | Phosphoribosylamine--glycine ligase; Similar to SP:P12039; identified by sequence similarity; putative; Belongs to the GARS family. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.999 |
purD | purQ | EF_1777 | EF_1783 | Phosphoribosylamine--glycine ligase; Similar to SP:P12039; identified by sequence similarity; putative; Belongs to the GARS family. | Phosphoribosylformylglycinamidine synthetase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.999 |
purD | purS | EF_1777 | EF_1784 | Phosphoribosylamine--glycine ligase; Similar to SP:P12039; identified by sequence similarity; putative; Belongs to the GARS family. | Phosphoribosylformylglycinamidine synthase, PurS protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] | 0.987 |