STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EF_2901D-isomer specific 2-hydroxyacid dehydrogenase family protein; Similar to GP:10173564; identified by sequence similarity; putative; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (320 aa)    
Predicted Functional Partners:
udk
Uridine kinase; Identified by match to PFAM protein family HMM PF01121.
   
 0.935
maf
Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
  
   0.649
sodA
Superoxide dismutase, Mn; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the iron/manganese superoxide dismutase family.
     
 0.648
EF_0462
Conserved domain protein; Similar to SP:P54485; identified by sequence similarity; putative.
       0.635
EF_2627
Teichoic acid glycosylation protein, putative; Similar to GP:8886146; identified by sequence similarity; putative.
       0.635
adhE
Aldehyde-alcohol dehydrogenase; Similar to SP:P17547, SP:P33008, and PID:151586; identified by sequence similarity; putative; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 
 0.619
thrC
Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.
  
  
 0.574
EF_2900
Hypothetical protein; Identified by Glimmer2; putative.
       0.572
rplV
Ribosomal protein L22; This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).
   
 
 0.571
hom
Homoserine dehydrogenase; Similar to GB:X66975, GB:X60648, GB:X65371, GB:X62006, GB:X65372, SP:P26599, PID:32354, PID:35770, PID:35772, GB:X66975, GB:X60648, GB:X65371, GB:X62006, GB:X65372, SP:P26599, PID:32354, PID:35770, and PID:35772; identified by sequence similarity; putative.
  
 
 0.557
Your Current Organism:
Enterococcus faecalis V583
NCBI taxonomy Id: 226185
Other names: E. faecalis V583, Enterococcus faecalis str. V583, Enterococcus faecalis strain V583
Server load: low (24%) [HD]