node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EF_0669 | murE | EF_0669 | EF_0668 | Polysaccharide biosynthesis family protein; Similar to GP:4090864, SP:P24178, GB:X57403, PID:41233, GB:U00096, and PID:1788815; identified by sequence similarity; putative. | UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase, putative; Catalyzes the addition of L-lysine to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. | 0.844 |
EF_0669 | pbpC | EF_0669 | EF_0991 | Polysaccharide biosynthesis family protein; Similar to GP:4090864, SP:P24178, GB:X57403, PID:41233, GB:U00096, and PID:1788815; identified by sequence similarity; putative. | Penicillin-binding protein C; Similar to SP:P13551, GB:X52165, SP:P13551, and GB:X52165; identified by sequence similarity; putative. | 0.429 |
EF_2586 | murE | EF_2586 | EF_0668 | Cobyric acid synthase, putative; Similar to GP:3820538; identified by sequence similarity; putative. | UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase, putative; Catalyzes the addition of L-lysine to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. | 0.805 |
EF_2586 | murG | EF_2586 | EF_0994 | Cobyric acid synthase, putative; Similar to GP:3820538; identified by sequence similarity; putative. | UDPdiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.904 |
mraY | murB | EF_0992 | EF_2733 | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.590 |
mraY | murB-2 | EF_0992 | EF_2489 | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | MurB family protein; Cell wall formation. | 0.522 |
mraY | murC | EF_0992 | EF_1908 | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.883 |
mraY | murD | EF_0992 | EF_0993 | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.991 |
mraY | murE | EF_0992 | EF_0668 | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase, putative; Catalyzes the addition of L-lysine to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. | 0.786 |
mraY | murF | EF_0992 | EF_0845 | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.990 |
mraY | murG | EF_0992 | EF_0994 | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | UDPdiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.997 |
mraY | pbpC | EF_0992 | EF_0991 | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | Penicillin-binding protein C; Similar to SP:P13551, GB:X52165, SP:P13551, and GB:X52165; identified by sequence similarity; putative. | 0.936 |
murB | mraY | EF_2733 | EF_0992 | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.590 |
murB | murB-2 | EF_2733 | EF_2489 | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | MurB family protein; Cell wall formation. | 0.912 |
murB | murC | EF_2733 | EF_1908 | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.998 |
murB | murD | EF_2733 | EF_0993 | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.897 |
murB | murE | EF_2733 | EF_0668 | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase, putative; Catalyzes the addition of L-lysine to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. | 0.923 |
murB | murF | EF_2733 | EF_0845 | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.935 |
murB | murG | EF_2733 | EF_0994 | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | UDPdiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.899 |
murB | pbpC | EF_2733 | EF_0991 | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | Penicillin-binding protein C; Similar to SP:P13551, GB:X52165, SP:P13551, and GB:X52165; identified by sequence similarity; putative. | 0.569 |