node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EF_1918 | clpX | EF_1918 | EF_1917 | Conserved hypothetical protein; Similar to SP:O86281; identified by sequence similarity; putative. | ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.809 |
EF_1918 | engB | EF_1918 | EF_1916 | Conserved hypothetical protein; Similar to SP:O86281; identified by sequence similarity; putative. | GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | 0.488 |
atpD | clpX | EF_2608 | EF_1917 | ATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. | ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.770 |
atpD | ftsH | EF_2608 | EF_0265 | ATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. | Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.403 |
atpD | groEL | EF_2608 | EF_2633 | ATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. | Chaperonin, 60 kDa; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.515 |
atpD | tig | EF_2608 | EF_0715 | ATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. | Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. | 0.514 |
clpC | clpE | EF_3282 | EF_0706 | ATP-dependent Clp protease, ATP-binding subunit ClpC; Similar to GB:X57204, and PID:457413; identified by sequence similarity; putative; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease, ATP-binding subunit ClpE; Similar to GP:4103470, and GP:4103470; identified by sequence similarity; putative; Belongs to the ClpA/ClpB family. | 0.489 |
clpC | clpP | EF_3282 | EF_0771 | ATP-dependent Clp protease, ATP-binding subunit ClpC; Similar to GB:X57204, and PID:457413; identified by sequence similarity; putative; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.966 |
clpC | clpX | EF_3282 | EF_1917 | ATP-dependent Clp protease, ATP-binding subunit ClpC; Similar to GB:X57204, and PID:457413; identified by sequence similarity; putative; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.876 |
clpC | ftsH | EF_3282 | EF_0265 | ATP-dependent Clp protease, ATP-binding subunit ClpC; Similar to GB:X57204, and PID:457413; identified by sequence similarity; putative; Belongs to the ClpA/ClpB family. | Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.507 |
clpC | groEL | EF_3282 | EF_2633 | ATP-dependent Clp protease, ATP-binding subunit ClpC; Similar to GB:X57204, and PID:457413; identified by sequence similarity; putative; Belongs to the ClpA/ClpB family. | Chaperonin, 60 kDa; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.747 |
clpC | hslV | EF_3282 | EF_1647 | ATP-dependent Clp protease, ATP-binding subunit ClpC; Similar to GB:X57204, and PID:457413; identified by sequence similarity; putative; Belongs to the ClpA/ClpB family. | Heat shock protein HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.717 |
clpE | clpC | EF_0706 | EF_3282 | ATP-dependent Clp protease, ATP-binding subunit ClpE; Similar to GP:4103470, and GP:4103470; identified by sequence similarity; putative; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease, ATP-binding subunit ClpC; Similar to GB:X57204, and PID:457413; identified by sequence similarity; putative; Belongs to the ClpA/ClpB family. | 0.489 |
clpE | clpP | EF_0706 | EF_0771 | ATP-dependent Clp protease, ATP-binding subunit ClpE; Similar to GP:4103470, and GP:4103470; identified by sequence similarity; putative; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.981 |
clpE | clpX | EF_0706 | EF_1917 | ATP-dependent Clp protease, ATP-binding subunit ClpE; Similar to GP:4103470, and GP:4103470; identified by sequence similarity; putative; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.876 |
clpE | groEL | EF_0706 | EF_2633 | ATP-dependent Clp protease, ATP-binding subunit ClpE; Similar to GP:4103470, and GP:4103470; identified by sequence similarity; putative; Belongs to the ClpA/ClpB family. | Chaperonin, 60 kDa; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.767 |
clpE | hslV | EF_0706 | EF_1647 | ATP-dependent Clp protease, ATP-binding subunit ClpE; Similar to GP:4103470, and GP:4103470; identified by sequence similarity; putative; Belongs to the ClpA/ClpB family. | Heat shock protein HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.489 |
clpP | clpC | EF_0771 | EF_3282 | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | ATP-dependent Clp protease, ATP-binding subunit ClpC; Similar to GB:X57204, and PID:457413; identified by sequence similarity; putative; Belongs to the ClpA/ClpB family. | 0.966 |
clpP | clpE | EF_0771 | EF_0706 | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | ATP-dependent Clp protease, ATP-binding subunit ClpE; Similar to GP:4103470, and GP:4103470; identified by sequence similarity; putative; Belongs to the ClpA/ClpB family. | 0.981 |
clpP | clpX | EF_0771 | EF_1917 | ATP-dependent Clp protease, proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. | 0.999 |