node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BT_1375 | BT_1376 | BT_1375 | BT_1376 | Aspartokinase; Belongs to the aspartokinase family. | Putative ATP-binding protein involved in cell division. | 0.835 |
BT_1375 | dapA | BT_1375 | BT_0895 | Aspartokinase; Belongs to the aspartokinase family. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.454 |
BT_1375 | hisF | BT_1375 | BT_1378 | Aspartokinase; Belongs to the aspartokinase family. | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.847 |
BT_1375 | hisI | BT_1375 | BT_1377 | Aspartokinase; Belongs to the aspartokinase family. | phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase; In the C-terminal section; belongs to the PRA-PH family. | 0.903 |
BT_1375 | lysA | BT_1375 | BT_1374 | Aspartokinase; Belongs to the aspartokinase family. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.977 |
BT_1376 | BT_1375 | BT_1376 | BT_1375 | Putative ATP-binding protein involved in cell division. | Aspartokinase; Belongs to the aspartokinase family. | 0.835 |
BT_1376 | hisF | BT_1376 | BT_1378 | Putative ATP-binding protein involved in cell division. | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.748 |
BT_1376 | hisI | BT_1376 | BT_1377 | Putative ATP-binding protein involved in cell division. | phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase; In the C-terminal section; belongs to the PRA-PH family. | 0.846 |
BT_1376 | lysA | BT_1376 | BT_1374 | Putative ATP-binding protein involved in cell division. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.719 |
BT_1979 | dapF | BT_1979 | BT_0548 | Meso-diaminopimelate D-dehydrogenase; Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.937 |
BT_1979 | lysA | BT_1979 | BT_1374 | Meso-diaminopimelate D-dehydrogenase; Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.912 |
BT_1979 | murE | BT_1979 | BT_3452 | Meso-diaminopimelate D-dehydrogenase; Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate. | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.901 |
BT_4474 | BT_4612 | BT_4474 | BT_4612 | Conserved hypothetical protein; L-lysine 2,3-aminomutase-like. | Saccharopine dehydrogenase. | 0.900 |
BT_4474 | lysA | BT_4474 | BT_1374 | Conserved hypothetical protein; L-lysine 2,3-aminomutase-like. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.808 |
BT_4612 | BT_4474 | BT_4612 | BT_4474 | Saccharopine dehydrogenase. | Conserved hypothetical protein; L-lysine 2,3-aminomutase-like. | 0.900 |
BT_4612 | lysA | BT_4612 | BT_1374 | Saccharopine dehydrogenase. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.921 |
dapA | BT_1375 | BT_0895 | BT_1375 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Aspartokinase; Belongs to the aspartokinase family. | 0.454 |
dapA | dapF | BT_0895 | BT_0548 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.588 |
dapA | lysA | BT_0895 | BT_1374 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.758 |
dapF | BT_1979 | BT_0548 | BT_1979 | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Meso-diaminopimelate D-dehydrogenase; Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate. | 0.937 |