node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BT_1362 | dut | BT_1362 | BT_3461 | Flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.886 |
BT_1998 | Ndk | BT_1998 | BT_3925 | Anaerobic ribonucleoside-triphosphate reductase. | Nucleoside diphosphate kinase; Belongs to the NDK family. | 0.912 |
BT_1998 | dut | BT_1998 | BT_3461 | Anaerobic ribonucleoside-triphosphate reductase. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.921 |
BT_2440 | BT_4260 | BT_2440 | BT_4260 | 5'-nucleotidase precursor. | Deoxycytidylate deaminase. | 0.907 |
BT_2440 | dut | BT_2440 | BT_3461 | 5'-nucleotidase precursor. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.901 |
BT_2440 | surE | BT_2440 | BT_4003 | 5'-nucleotidase precursor. | Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.912 |
BT_2440 | tdk | BT_2440 | BT_2275 | 5'-nucleotidase precursor. | Thymidine kinase. | 0.933 |
BT_2440 | thyA | BT_2440 | BT_2047 | 5'-nucleotidase precursor. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.908 |
BT_3462 | BT_3464 | BT_3462 | BT_3464 | TPR domain protein. | Zinc metalloendopeptidase-like. | 0.915 |
BT_3462 | dut | BT_3462 | BT_3461 | TPR domain protein. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.855 |
BT_3464 | BT_3462 | BT_3464 | BT_3462 | Zinc metalloendopeptidase-like. | TPR domain protein. | 0.915 |
BT_3464 | dut | BT_3464 | BT_3461 | Zinc metalloendopeptidase-like. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.827 |
BT_4260 | BT_2440 | BT_4260 | BT_2440 | Deoxycytidylate deaminase. | 5'-nucleotidase precursor. | 0.907 |
BT_4260 | dut | BT_4260 | BT_3461 | Deoxycytidylate deaminase. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.944 |
BT_4260 | surE | BT_4260 | BT_4003 | Deoxycytidylate deaminase. | Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.901 |
BT_4260 | tdk | BT_4260 | BT_2275 | Deoxycytidylate deaminase. | Thymidine kinase. | 0.931 |
BT_4260 | thyA | BT_4260 | BT_2047 | Deoxycytidylate deaminase. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.937 |
Ndk | BT_1998 | BT_3925 | BT_1998 | Nucleoside diphosphate kinase; Belongs to the NDK family. | Anaerobic ribonucleoside-triphosphate reductase. | 0.912 |
Ndk | dut | BT_3925 | BT_3461 | Nucleoside diphosphate kinase; Belongs to the NDK family. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.929 |
dut | BT_1362 | BT_3461 | BT_1362 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | Flavoprotein; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.886 |