node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BC_0254 | kynA | BC_0254 | BC_2757 | Homogentisate 1,2-dioxygenase. | Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.443 |
BC_0254 | kynU | BC_0254 | BC_2759 | Homogentisate 1,2-dioxygenase. | L-kynurenine hydrolase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.626 |
BC_0395 | kynA | BC_0395 | BC_2757 | Metal-dependent hydrolase. | Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.420 |
BC_0395 | kynU | BC_0395 | BC_2759 | Metal-dependent hydrolase. | L-kynurenine hydrolase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.774 |
BC_0767 | kynA | BC_0767 | BC_2757 | Methylthioribose transport ATP-binding protein. | Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.592 |
BC_0767 | kynU | BC_0767 | BC_2759 | Methylthioribose transport ATP-binding protein. | L-kynurenine hydrolase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.591 |
BC_0863 | BC_1155 | BC_0863 | BC_1155 | Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide. | Catalase; Belongs to the catalase family. | 0.906 |
BC_0863 | BC_3008 | BC_0863 | BC_3008 | Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide. | Catalase. | 0.912 |
BC_0863 | kynU | BC_0863 | BC_2759 | Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide. | L-kynurenine hydrolase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.903 |
BC_1155 | BC_0863 | BC_1155 | BC_0863 | Catalase; Belongs to the catalase family. | Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide. | 0.906 |
BC_1155 | BC_3008 | BC_1155 | BC_3008 | Catalase; Belongs to the catalase family. | Catalase. | 0.909 |
BC_1155 | kynU | BC_1155 | BC_2759 | Catalase; Belongs to the catalase family. | L-kynurenine hydrolase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.903 |
BC_2760 | kynA | BC_2760 | BC_2757 | Transcriptional regulator, TetR family. | Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | 0.614 |
BC_2760 | kynB | BC_2760 | BC_2758 | Transcriptional regulator, TetR family. | Metal-dependent hydrolase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. | 0.648 |
BC_2760 | kynU | BC_2760 | BC_2759 | Transcriptional regulator, TetR family. | L-kynurenine hydrolase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.593 |
BC_3008 | BC_0863 | BC_3008 | BC_0863 | Catalase. | Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide. | 0.912 |
BC_3008 | BC_1155 | BC_3008 | BC_1155 | Catalase. | Catalase; Belongs to the catalase family. | 0.909 |
BC_3008 | kynU | BC_3008 | BC_2759 | Catalase. | L-kynurenine hydrolase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. | 0.903 |
kynA | BC_0254 | BC_2757 | BC_0254 | Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | Homogentisate 1,2-dioxygenase. | 0.443 |
kynA | BC_0395 | BC_2757 | BC_0395 | Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. | Metal-dependent hydrolase. | 0.420 |