node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BC_0621 | BC_1610 | BC_0621 | BC_1610 | 2-amino-3-ketobutyrate coenzyme A ligase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.471 |
BC_0621 | BC_2245 | BC_0621 | BC_2245 | 2-amino-3-ketobutyrate coenzyme A ligase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. | 6-acetamido-3-oxohexanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.471 |
BC_0621 | bioA | BC_0621 | BC_4119 | 2-amino-3-ketobutyrate coenzyme A ligase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | 0.586 |
BC_0621 | bioB | BC_0621 | BC_4114 | 2-amino-3-ketobutyrate coenzyme A ligase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.796 |
BC_0621 | bioC | BC_0621 | BC_4115 | 2-amino-3-ketobutyrate coenzyme A ligase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. | Biotin synthesis protein bioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.591 |
BC_0621 | bioD | BC_0621 | BC_4118 | 2-amino-3-ketobutyrate coenzyme A ligase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.885 |
BC_0621 | birA | BC_0621 | BC_1537 | 2-amino-3-ketobutyrate coenzyme A ligase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. | Biotin operon repressor / Biotin--[acetyl-CoA-carboxylase] synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.519 |
BC_1610 | BC_0621 | BC_1610 | BC_0621 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 2-amino-3-ketobutyrate coenzyme A ligase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. | 0.471 |
BC_1610 | bioB | BC_1610 | BC_4114 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.755 |
BC_1610 | bioD | BC_1610 | BC_4118 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.737 |
BC_1610 | bioF | BC_1610 | BC_4117 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.482 |
BC_1610 | birA | BC_1610 | BC_1537 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Biotin operon repressor / Biotin--[acetyl-CoA-carboxylase] synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.491 |
BC_2245 | BC_0621 | BC_2245 | BC_0621 | 6-acetamido-3-oxohexanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 2-amino-3-ketobutyrate coenzyme A ligase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. | 0.471 |
BC_2245 | bioB | BC_2245 | BC_4114 | 6-acetamido-3-oxohexanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.737 |
BC_2245 | bioD | BC_2245 | BC_4118 | 6-acetamido-3-oxohexanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.730 |
BC_2245 | bioF | BC_2245 | BC_4117 | 6-acetamido-3-oxohexanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.472 |
BC_2245 | birA | BC_2245 | BC_1537 | 6-acetamido-3-oxohexanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Biotin operon repressor / Biotin--[acetyl-CoA-carboxylase] synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.491 |
BC_4116 | BC_4120 | BC_4116 | BC_4120 | BioH protein. | Hypothetical protein. | 0.524 |
BC_4116 | bioA | BC_4116 | BC_4119 | BioH protein. | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | 0.957 |
BC_4116 | bioB | BC_4116 | BC_4114 | BioH protein. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.887 |