STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ompP1Outer membrane porin P1; Able to form a pore in lipid bilayers. (252 aa)    
Predicted Functional Partners:
CBU_0307
Outer membrane protein; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
     
 0.788
com1
Outer membrane protein.
      
 0.569
CBU_1379a
Hypothetical protein; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
     
  0.540
CBU_1869
Hypothetical exported protein.
      
 0.440
dnaQ
DNA polymerase III, epsilon chain; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.
      
 0.437
tag
DNA-3-methyladenine glycosylase.
      
 0.434
htpG
Chaperone protein; Molecular chaperone. Has ATPase activity; Belongs to the heat shock protein 90 family.
       0.418
CBU_1224a
Hypothetical protein.
      
 0.416
pfp
Pyrophosphate--fructose 6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
      
 0.416
fkpA
FKBP-type peptidyl-prolyl cis-trans isomerase; May be an essential virulence factor associated with macrophage infectivity. Exhibits PPIase activity.
      
 0.410
Your Current Organism:
Coxiella burnetii
NCBI taxonomy Id: 227377
Other names: C. burnetii RSA 493, Coxiella burnetii RSA 493, Coxiella burnetii str. RSA 493
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.