node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CBU_0749 | CBU_0750 | CBU_0749 | CBU_0750 | 3-deoxy-manno-octulosonate-8-phosphatase; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. | Arabinose-5-phosphate isomerase. | 0.996 |
CBU_0749 | kdsA | CBU_0749 | CBU_1675 | 3-deoxy-manno-octulosonate-8-phosphatase; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | 0.994 |
CBU_0749 | kdsB | CBU_0749 | CBU_0479 | 3-deoxy-manno-octulosonate-8-phosphatase; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.996 |
CBU_0750 | CBU_0749 | CBU_0750 | CBU_0749 | Arabinose-5-phosphate isomerase. | 3-deoxy-manno-octulosonate-8-phosphatase; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. | 0.996 |
CBU_0750 | kdsA | CBU_0750 | CBU_1675 | Arabinose-5-phosphate isomerase. | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | 0.991 |
CBU_0750 | kdsB | CBU_0750 | CBU_0479 | Arabinose-5-phosphate isomerase. | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.906 |
CBU_0750 | kdtA | CBU_0750 | CBU_0063 | Arabinose-5-phosphate isomerase. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.791 |
CBU_0750 | lpxB | CBU_0750 | CBU_0620 | Arabinose-5-phosphate isomerase. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.678 |
CBU_0750 | lpxK | CBU_0750 | CBU_0857 | Arabinose-5-phosphate isomerase. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.801 |
dapA | kdsA | CBU_1222 | CBU_1675 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | 0.855 |
dapA | lpxB | CBU_1222 | CBU_0620 | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.651 |
eno | kdsA | CBU_1674 | CBU_1675 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | 0.658 |
hemK | kdsA | CBU_1964 | CBU_1675 | Peptide release factor-glutamine N5-methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | 0.668 |
kdsA | CBU_0749 | CBU_1675 | CBU_0749 | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | 3-deoxy-manno-octulosonate-8-phosphatase; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. | 0.994 |
kdsA | CBU_0750 | CBU_1675 | CBU_0750 | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | Arabinose-5-phosphate isomerase. | 0.991 |
kdsA | dapA | CBU_1675 | CBU_1222 | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.855 |
kdsA | eno | CBU_1675 | CBU_1674 | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. | 0.658 |
kdsA | hemK | CBU_1675 | CBU_1964 | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | Peptide release factor-glutamine N5-methyltransferase; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | 0.668 |
kdsA | kdsB | CBU_1675 | CBU_0479 | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | 3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.844 |
kdsA | kdtA | CBU_1675 | CBU_0063 | 2-dehydro-3-deoxyphosphooctonate aldolase; Belongs to the KdsA family. | 3-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.689 |