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STRINGSTRING
rnc protein (Streptomyces avermitilis) - STRING interaction network
"rnc" - Ribonuclease 3 in Streptomyces avermitilis
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rncRibonuclease 3; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism (276 aa)    
Predicted Functional Partners:
rpmF
PF01783- Ribosomal L32p protein family; Belongs to the bacterial ribosomal protein bL32 family (57 aa)
   
 
  0.963
SAV_2667
PF02620- Uncharacterized ACR, COG1399 (217 aa)
   
   
  0.924
rpsO
30S ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA (95 aa)
 
 
  0.894
rpsG
30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (156 aa)
 
 
  0.881
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (1161 aa)
   
   
  0.881
rpsB
PF00318- Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family (308 aa)
 
 
  0.852
rpmA
PF01016- Ribosomal L27 protein; Belongs to the bacterial ribosomal protein bL27 family (84 aa)
 
 
  0.851
rpsP
PF00886- Ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family (142 aa)
 
 
  0.850
rpsE
30S ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy; Belongs to the universal ribosomal protein uS5 family (201 aa)
   
 
  0.848
rplD
50S ribosomal protein L4; One of the primary rRNA binding proteins, this protein initially binds near the 5’-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (221 aa)
   
 
  0.841
Your Current Organism:
Streptomyces avermitilis
NCBI taxonomy Id: 227882
Other names: S. avermitilis MA-4680 = NBRC 14893, Streptomyces avermitilis, Streptomyces avermitilis MA-4680, Streptomyces avermitilis MA-4680 = NBRC 14893, Streptomyces avermitilis NBRC 14893, Streptomyces avermitilis NBRC 14893 = MA-4680
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