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rnc protein (Streptomyces avermitilis) - STRING interaction network
"rnc" - Ribonuclease III in Streptomyces avermitilis
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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rncRibonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism (276 aa)    
Predicted Functional Partners:
rpmF
50S ribosomal protein L32 (57 aa)
         
  0.854
SAV_2667
Hypothetical protein (217 aa)
   
   
  0.836
polA1
DNA polymerase I (907 aa)
 
   
  0.796
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (622 aa)
 
 
  0.793
fpg
formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3’- and 5’-phosphates (286 aa)
   
   
  0.793
rpsB
30S ribosomal protein S2 (308 aa)
 
 
  0.768
mnmA
tRNA-specific 2-thiouridylase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (376 aa)
 
   
  0.750
rplS
50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (116 aa)
   
 
  0.738
SAV_3103
Hypothetical protein (288 aa)
            0.728
rpmB1
50S ribosomal protein L28 (61 aa)
   
 
  0.726
Your Current Organism:
Streptomyces avermitilis
NCBI taxonomy Id: 227882
Other names: S. avermitilis, S. avermitilis MA-4680, Streptomyces avermectinius, Streptomyces avermectinius Takahashi et al. 2002, Streptomyces avermitilis, Streptomyces avermitilis MA-4680, Streptomyces avermitilis str. MA-4680
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