STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (254 aa)    
Predicted Functional Partners:
gap
Glyceraldehyde 3-phosphate dehydrogenase; Similar to GB:L14017, and PID:295162; identified by sequence similarity; putative; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 
 0.995
pgk
Phosphoglycerate kinase; Similar to GB:M88334, SP:P25526, PID:147901, GB:U00096, and PID:1789015; identified by sequence similarity; putative; Belongs to the phosphoglycerate kinase family.
 
 0.992
pgi
Glucose-6-phosphate isomerase; Similar to GP:8979398; identified by sequence similarity; putative.
  
 0.975
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 
 0.931
fbaB
Fructose-bisphosphate aldolase class I; Similar to GB:M17643, SP:P10728, PID:143614, PID:1303999, and GB:AL009126; identified by sequence similarity; putative.
  
 
 0.930
pyk
Pyruvate kinase; Identified by match to PFAM protein family HMM PF02887; Belongs to the pyruvate kinase family.
 
  
 0.924
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
  
 0.918
tkt
Transketolase; Identified by match to PFAM protein family HMM PF02779; Belongs to the transketolase family.
  
 0.911
zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
   
 
 0.853
gpmA
Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
  
 
 0.847
Your Current Organism:
Chlamydia caviae
NCBI taxonomy Id: 227941
Other names: C. caviae GPIC, Chlamydia caviae GPIC, Chlamydophila caviae GPIC, Chlamydophila caviae str. GPIC
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.