node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NE1486 | NE1487 | NE1486 | NE1487 | Aminotransferases class-IV. | Conserved hypothetical protein; COGs COG2921; Belongs to the UPF0250 family. | 0.852 |
NE1486 | NE2157 | NE1486 | NE2157 | Aminotransferases class-IV. | Dihydrolipoamide dehydrogenase. | 0.448 |
NE1486 | lipA | NE1486 | NE1489 | Aminotransferases class-IV. | Lipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.557 |
NE1486 | lipB | NE1486 | NE1488 | Aminotransferases class-IV. | lipB: lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.560 |
NE1487 | NE1486 | NE1487 | NE1486 | Conserved hypothetical protein; COGs COG2921; Belongs to the UPF0250 family. | Aminotransferases class-IV. | 0.852 |
NE1487 | lipA | NE1487 | NE1489 | Conserved hypothetical protein; COGs COG2921; Belongs to the UPF0250 family. | Lipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.630 |
NE1487 | lipB | NE1487 | NE1488 | Conserved hypothetical protein; COGs COG2921; Belongs to the UPF0250 family. | lipB: lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.745 |
NE2157 | NE1486 | NE2157 | NE1486 | Dihydrolipoamide dehydrogenase. | Aminotransferases class-IV. | 0.448 |
NE2157 | aceF | NE2157 | NE0360 | Dihydrolipoamide dehydrogenase. | aceF; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.985 |
NE2157 | gcvH1 | NE2157 | NE0608 | Dihydrolipoamide dehydrogenase. | Glycine cleavage H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.992 |
NE2157 | guaA | NE2157 | NE0094 | Dihydrolipoamide dehydrogenase. | guaA; Catalyzes the synthesis of GMP from XMP. | 0.524 |
NE2157 | lipA | NE2157 | NE1489 | Dihydrolipoamide dehydrogenase. | Lipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.712 |
NE2157 | lipB | NE2157 | NE1488 | Dihydrolipoamide dehydrogenase. | lipB: lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.660 |
NE2157 | lpdA3 | NE2157 | NE2319 | Dihydrolipoamide dehydrogenase. | pdA3; dihydrolipoamide dehydrogenase E3 component. | 0.981 |
NE2157 | sucB | NE2157 | NE2375 | Dihydrolipoamide dehydrogenase. | sucB; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.987 |
aceF | NE2157 | NE0360 | NE2157 | aceF; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Dihydrolipoamide dehydrogenase. | 0.985 |
aceF | gcvH1 | NE0360 | NE0608 | aceF; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Glycine cleavage H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.706 |
aceF | lipA | NE0360 | NE1489 | aceF; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Lipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.553 |
aceF | lipB | NE0360 | NE1488 | aceF; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | lipB: lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.521 |
aceF | lpdA3 | NE0360 | NE2319 | aceF; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | pdA3; dihydrolipoamide dehydrogenase E3 component. | 0.993 |