node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NE2311 | NE2520 | NE2311 | NE2520 | Possible helicase (Snf2/Rad54 family). | ATP-dependent DNA helicase RecQ. | 0.681 |
NE2311 | RecQ | NE2311 | NE0093 | Possible helicase (Snf2/Rad54 family). | recQ; ATP-dependent DNA helicase. | 0.968 |
NE2311 | dnaN | NE2311 | NE0002 | Possible helicase (Snf2/Rad54 family). | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | 0.919 |
NE2311 | polA | NE2311 | NE1468 | Possible helicase (Snf2/Rad54 family). | polA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.960 |
NE2311 | recA | NE2311 | NE1932 | Possible helicase (Snf2/Rad54 family). | RecA bacterial DNA recombination protein:AAA ATPase superfamily; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.865 |
NE2311 | sbcD | NE2311 | NE1390 | Possible helicase (Snf2/Rad54 family). | Serine/threonine specific protein phosphatase:Exonuclease SbcD; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | 0.552 |
NE2311 | topB | NE2311 | NE1966 | Possible helicase (Snf2/Rad54 family). | topB; DNA topoisomerase III protein. | 0.643 |
NE2311 | uvrD | NE2311 | NE1473 | Possible helicase (Snf2/Rad54 family). | UvrD/REP helicase. | 0.451 |
NE2520 | NE2311 | NE2520 | NE2311 | ATP-dependent DNA helicase RecQ. | Possible helicase (Snf2/Rad54 family). | 0.681 |
NE2520 | RecQ | NE2520 | NE0093 | ATP-dependent DNA helicase RecQ. | recQ; ATP-dependent DNA helicase. | 0.975 |
NE2520 | dnaN | NE2520 | NE0002 | ATP-dependent DNA helicase RecQ. | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | 0.410 |
NE2520 | polA | NE2520 | NE1468 | ATP-dependent DNA helicase RecQ. | polA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.933 |
NE2520 | radA | NE2520 | NE1808 | ATP-dependent DNA helicase RecQ. | Sms: DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.538 |
NE2520 | recA | NE2520 | NE1932 | ATP-dependent DNA helicase RecQ. | RecA bacterial DNA recombination protein:AAA ATPase superfamily; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.869 |
NE2520 | sbcD | NE2520 | NE1390 | ATP-dependent DNA helicase RecQ. | Serine/threonine specific protein phosphatase:Exonuclease SbcD; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | 0.819 |
NE2520 | topB | NE2520 | NE1966 | ATP-dependent DNA helicase RecQ. | topB; DNA topoisomerase III protein. | 0.896 |
NE2520 | uvrD | NE2520 | NE1473 | ATP-dependent DNA helicase RecQ. | UvrD/REP helicase. | 0.705 |
RecQ | NE2311 | NE0093 | NE2311 | recQ; ATP-dependent DNA helicase. | Possible helicase (Snf2/Rad54 family). | 0.968 |
RecQ | NE2520 | NE0093 | NE2520 | recQ; ATP-dependent DNA helicase. | ATP-dependent DNA helicase RecQ. | 0.975 |
RecQ | dnaN | NE0093 | NE0002 | recQ; ATP-dependent DNA helicase. | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | 0.970 |