node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NE0191 | ampG | NE0191 | NE2191 | Domain of unknown function DUF227. | Putative transport transmembrane protein. | 0.428 |
NE0191 | nagZ | NE0191 | NE2320 | Domain of unknown function DUF227. | Glycoside hydrolase family 3, N terminal; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.931 |
acpS | era | NE2321 | NE2323 | acpS: holo-(acyl-carrier-protein) synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. | Type 2 KH domain; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.691 |
acpS | lpdA3 | NE2321 | NE2319 | acpS: holo-(acyl-carrier-protein) synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. | pdA3; dihydrolipoamide dehydrogenase E3 component. | 0.725 |
acpS | nagZ | NE2321 | NE2320 | acpS: holo-(acyl-carrier-protein) synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. | Glycoside hydrolase family 3, N terminal; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.876 |
acpS | pdxJ | NE2321 | NE2322 | acpS: holo-(acyl-carrier-protein) synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. | Pyridoxal phosphate biosynthetic protein PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.889 |
ampD | ampG | NE2182 | NE2191 | N-acetylmuramoyl-L-alanine amidase (family 2). | Putative transport transmembrane protein. | 0.865 |
ampD | anmK | NE2182 | NE1429 | N-acetylmuramoyl-L-alanine amidase (family 2). | Conserved hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.866 |
ampD | murA | NE2182 | NE1852 | N-acetylmuramoyl-L-alanine amidase (family 2). | EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.491 |
ampD | murB | NE2182 | NE0993 | N-acetylmuramoyl-L-alanine amidase (family 2). | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.493 |
ampD | nagZ | NE2182 | NE2320 | N-acetylmuramoyl-L-alanine amidase (family 2). | Glycoside hydrolase family 3, N terminal; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.856 |
ampG | NE0191 | NE2191 | NE0191 | Putative transport transmembrane protein. | Domain of unknown function DUF227. | 0.428 |
ampG | ampD | NE2191 | NE2182 | Putative transport transmembrane protein. | N-acetylmuramoyl-L-alanine amidase (family 2). | 0.865 |
ampG | anmK | NE2191 | NE1429 | Putative transport transmembrane protein. | Conserved hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.853 |
ampG | murA | NE2191 | NE1852 | Putative transport transmembrane protein. | EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.472 |
ampG | murB | NE2191 | NE0993 | Putative transport transmembrane protein. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.451 |
ampG | nagZ | NE2191 | NE2320 | Putative transport transmembrane protein. | Glycoside hydrolase family 3, N terminal; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.885 |
anmK | ampD | NE1429 | NE2182 | Conserved hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | N-acetylmuramoyl-L-alanine amidase (family 2). | 0.866 |
anmK | ampG | NE1429 | NE2191 | Conserved hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Putative transport transmembrane protein. | 0.853 |
anmK | murA | NE1429 | NE1852 | Conserved hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.816 |