node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NE2549 | NE2550 | NE2549 | NE2550 | ATPase component ABC-type multidrug transport system. | Putative ABC-2 type transport system permease protein. | 0.991 |
NE2549 | NE2551 | NE2549 | NE2551 | ATPase component ABC-type multidrug transport system. | Conserved hypothetical protein. | 0.945 |
NE2549 | mutM,fpg | NE2549 | NE2552 | ATPase component ABC-type multidrug transport system. | Formamidopyrimidine-DNA glycolase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.657 |
NE2550 | NE2549 | NE2550 | NE2549 | Putative ABC-2 type transport system permease protein. | ATPase component ABC-type multidrug transport system. | 0.991 |
NE2550 | NE2551 | NE2550 | NE2551 | Putative ABC-2 type transport system permease protein. | Conserved hypothetical protein. | 0.966 |
NE2550 | mutM,fpg | NE2550 | NE2552 | Putative ABC-2 type transport system permease protein. | Formamidopyrimidine-DNA glycolase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.663 |
NE2551 | NE2549 | NE2551 | NE2549 | Conserved hypothetical protein. | ATPase component ABC-type multidrug transport system. | 0.945 |
NE2551 | NE2550 | NE2551 | NE2550 | Conserved hypothetical protein. | Putative ABC-2 type transport system permease protein. | 0.966 |
NE2551 | mutM,fpg | NE2551 | NE2552 | Conserved hypothetical protein. | Formamidopyrimidine-DNA glycolase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.769 |
RecQ | mutM,fpg | NE0093 | NE2552 | recQ; ATP-dependent DNA helicase. | Formamidopyrimidine-DNA glycolase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.566 |
RecQ | nth | NE0093 | NE2223 | recQ; ATP-dependent DNA helicase. | HhH-GPD:Iron-sulfur cluster loop (FCL); DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.461 |
RecQ | polA | NE0093 | NE1468 | recQ; ATP-dependent DNA helicase. | polA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.990 |
RecQ | recN | NE0093 | NE1479 | recQ; ATP-dependent DNA helicase. | ABC transporter:DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.491 |
RecQ | uvrC | NE0093 | NE0933 | recQ; ATP-dependent DNA helicase. | uvrC Nuclease subunit of the excinuclease complex; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.717 |
coaE | msrA | NE0598 | NE1701 | Uncharacterized protein family UPF0038; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Possible msrA, pms; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.457 |
coaE | mutM,fpg | NE0598 | NE2552 | Uncharacterized protein family UPF0038; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Formamidopyrimidine-DNA glycolase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.910 |
coaE | polA | NE0598 | NE1468 | Uncharacterized protein family UPF0038; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | polA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.820 |
msrA | coaE | NE1701 | NE0598 | Possible msrA, pms; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | Uncharacterized protein family UPF0038; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.457 |
msrA | mutM,fpg | NE1701 | NE2552 | Possible msrA, pms; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | Formamidopyrimidine-DNA glycolase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.516 |
msrA | polA | NE1701 | NE1468 | Possible msrA, pms; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | polA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.987 |