STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NEQ044NEQ044; O-sialoglycoprotein endopeptidase [Methanosarcina acetivorans]; COG3642: Mn2+-dependent serine/threonine protein kinase; IPR000719: Eukaryotic protein kinase; IPR001472: Bipartite nuclear localization signal. (197 aa)    
Predicted Functional Partners:
kae1
NEQ493; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37; Belongs to the KAE1 / TsaD family.
    
 0.964
NEQ045
NEQ045; DNA topoisomerase I [Pyrococcus horikoshii]; COG0550: Topoisomerase IA; IPR000380: Prokaryotic DNA topoisomerase I; IPR002936: Toprim domain; IPR003601: DNA topoisomerase I ATP-binding domain; IPR003602: DNA topoisomerase I DNA-binding domain.
     
 0.814
NEQ046
NEQ046.
       0.773
leuS
NEQ239; Isoleucine tRNA synthetase [Methanococcus jannaschii]; COG0495: Leucyl-tRNA synthetase; COG0143: Methionyl-tRNA synthetase; IPR002300: t-RNA synthetase, class Ia; IPR002308: Cysteinyl-tRNA synthetase; IPR001412: Aminoacyl-transfer RNA synthetases class-I; Belongs to the class-I aminoacyl-tRNA synthetase family.
   
 
 0.691
NEQ043
NEQ043; Putative ribosomal protein.
       0.686
NEQ040
NEQ040; Hypothetical protein; IPR000326: PA-phosphatase related phosphoesterase.
       0.620
NEQ042
NEQ042; Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.
       0.620
rps24e
NEQ548; SSU ribosomal protein S24E [Methanococcus jannashii]; COG2004: Ribosomal protein S24E; IPR001976: Ribosomal protein S24e; Belongs to the eukaryotic ribosomal protein eS24 family.
  
    0.616
infB
NEQ498; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.
  
  
 0.611
NEQ050
NEQ050; Hypothetical protein; COG1708: Predicted nucleotidyltransferases; COG1579: Zn-ribbon protein, possibly nucleic acid-binding.
       0.595
Your Current Organism:
Nanoarchaeum equitans
NCBI taxonomy Id: 228908
Other names: Microarchaeum sp. Kin4-M, N. equitans Kin4-M, Nanoarchaeum equitans Kin4-M, Nanoarchaeum equitans str. Kin4-M
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