STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
endANEQ205; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp. (154 aa)    
Predicted Functional Partners:
NEQ261
NEQ261; Hypothetical protein; COG1676: tRNA splicing endonuclease; IPR002827: tRNA intron endonuclease.
    
   0.900
psmB
NEQ203; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
       0.708
dnaG
NEQ341; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.
  
 
   0.662
NEQ208
NEQ208; Arginyl-tRNA synthetase [Lactobacillus gasseri]; COG0018: Arginyl-tRNA synthetase; IPR002453: Beta tubulin; IPR001412: Aminoacyl-transfer RNA synthetases class-I; IPR001278: Arginyl-tRNA synthetase.
     
 0.615
cca
NEQ152; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
 
   
 0.569
NEQ212
NEQ212; Ribosomal protein 15A isolog [Pyrococcus furiosus]; COG1439: Predicted nucleic acid-binding protein, consists of a PIN domain and a Zn-ribbon module; IPR002851: Protein of unknown function DUF133.
  
    0.563
rpl15
NEQ317; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
  
     0.520
rnz
NEQ064; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family.
  
  
 0.505
NEQ206
NEQ206; Conserved hypothetical protein with predicted RNA binding PUA domain [Pyrobaculum aerophilum]; COG2016: PUA domain (predicted RNA-binding domain); IPR002478: PUA domain.
       0.498
spt5
NEQ540; Stimulates transcription elongation; Belongs to the archaeal Spt5 family.
 
     0.413
Your Current Organism:
Nanoarchaeum equitans
NCBI taxonomy Id: 228908
Other names: Microarchaeum sp. Kin4-M, N. equitans Kin4-M, Nanoarchaeum equitans Kin4-M, Nanoarchaeum equitans str. Kin4-M
Server load: low (26%) [HD]