node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NEQ206 | NEQ208 | NEQ206 | NEQ208 | NEQ206; Conserved hypothetical protein with predicted RNA binding PUA domain [Pyrobaculum aerophilum]; COG2016: PUA domain (predicted RNA-binding domain); IPR002478: PUA domain. | NEQ208; Arginyl-tRNA synthetase [Lactobacillus gasseri]; COG0018: Arginyl-tRNA synthetase; IPR002453: Beta tubulin; IPR001412: Aminoacyl-transfer RNA synthetases class-I; IPR001278: Arginyl-tRNA synthetase. | 0.773 |
NEQ206 | endA | NEQ206 | NEQ205 | NEQ206; Conserved hypothetical protein with predicted RNA binding PUA domain [Pyrobaculum aerophilum]; COG2016: PUA domain (predicted RNA-binding domain); IPR002478: PUA domain. | NEQ205; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp. | 0.498 |
NEQ206 | psmB | NEQ206 | NEQ203 | NEQ206; Conserved hypothetical protein with predicted RNA binding PUA domain [Pyrobaculum aerophilum]; COG2016: PUA domain (predicted RNA-binding domain); IPR002478: PUA domain. | NEQ203; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.415 |
NEQ208 | NEQ206 | NEQ208 | NEQ206 | NEQ208; Arginyl-tRNA synthetase [Lactobacillus gasseri]; COG0018: Arginyl-tRNA synthetase; IPR002453: Beta tubulin; IPR001412: Aminoacyl-transfer RNA synthetases class-I; IPR001278: Arginyl-tRNA synthetase. | NEQ206; Conserved hypothetical protein with predicted RNA binding PUA domain [Pyrobaculum aerophilum]; COG2016: PUA domain (predicted RNA-binding domain); IPR002478: PUA domain. | 0.773 |
NEQ208 | dnaG | NEQ208 | NEQ341 | NEQ208; Arginyl-tRNA synthetase [Lactobacillus gasseri]; COG0018: Arginyl-tRNA synthetase; IPR002453: Beta tubulin; IPR001412: Aminoacyl-transfer RNA synthetases class-I; IPR001278: Arginyl-tRNA synthetase. | NEQ341; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | 0.728 |
NEQ208 | endA | NEQ208 | NEQ205 | NEQ208; Arginyl-tRNA synthetase [Lactobacillus gasseri]; COG0018: Arginyl-tRNA synthetase; IPR002453: Beta tubulin; IPR001412: Aminoacyl-transfer RNA synthetases class-I; IPR001278: Arginyl-tRNA synthetase. | NEQ205; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp. | 0.615 |
NEQ208 | psmB | NEQ208 | NEQ203 | NEQ208; Arginyl-tRNA synthetase [Lactobacillus gasseri]; COG0018: Arginyl-tRNA synthetase; IPR002453: Beta tubulin; IPR001412: Aminoacyl-transfer RNA synthetases class-I; IPR001278: Arginyl-tRNA synthetase. | NEQ203; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.415 |
NEQ208 | rpl15 | NEQ208 | NEQ317 | NEQ208; Arginyl-tRNA synthetase [Lactobacillus gasseri]; COG0018: Arginyl-tRNA synthetase; IPR002453: Beta tubulin; IPR001412: Aminoacyl-transfer RNA synthetases class-I; IPR001278: Arginyl-tRNA synthetase. | NEQ317; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.770 |
NEQ208 | spt5 | NEQ208 | NEQ540 | NEQ208; Arginyl-tRNA synthetase [Lactobacillus gasseri]; COG0018: Arginyl-tRNA synthetase; IPR002453: Beta tubulin; IPR001412: Aminoacyl-transfer RNA synthetases class-I; IPR001278: Arginyl-tRNA synthetase. | NEQ540; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. | 0.910 |
NEQ212 | NEQ261 | NEQ212 | NEQ261 | NEQ212; Ribosomal protein 15A isolog [Pyrococcus furiosus]; COG1439: Predicted nucleic acid-binding protein, consists of a PIN domain and a Zn-ribbon module; IPR002851: Protein of unknown function DUF133. | NEQ261; Hypothetical protein; COG1676: tRNA splicing endonuclease; IPR002827: tRNA intron endonuclease. | 0.563 |
NEQ212 | endA | NEQ212 | NEQ205 | NEQ212; Ribosomal protein 15A isolog [Pyrococcus furiosus]; COG1439: Predicted nucleic acid-binding protein, consists of a PIN domain and a Zn-ribbon module; IPR002851: Protein of unknown function DUF133. | NEQ205; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp. | 0.563 |
NEQ261 | NEQ212 | NEQ261 | NEQ212 | NEQ261; Hypothetical protein; COG1676: tRNA splicing endonuclease; IPR002827: tRNA intron endonuclease. | NEQ212; Ribosomal protein 15A isolog [Pyrococcus furiosus]; COG1439: Predicted nucleic acid-binding protein, consists of a PIN domain and a Zn-ribbon module; IPR002851: Protein of unknown function DUF133. | 0.563 |
NEQ261 | dnaG | NEQ261 | NEQ341 | NEQ261; Hypothetical protein; COG1676: tRNA splicing endonuclease; IPR002827: tRNA intron endonuclease. | NEQ341; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | 0.569 |
NEQ261 | endA | NEQ261 | NEQ205 | NEQ261; Hypothetical protein; COG1676: tRNA splicing endonuclease; IPR002827: tRNA intron endonuclease. | NEQ205; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp. | 0.900 |
NEQ261 | rnz | NEQ261 | NEQ064 | NEQ261; Hypothetical protein; COG1676: tRNA splicing endonuclease; IPR002827: tRNA intron endonuclease. | NEQ064; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. | 0.505 |
cca | endA | NEQ152 | NEQ205 | NEQ152; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. | NEQ205; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp. | 0.569 |
cca | spt5 | NEQ152 | NEQ540 | NEQ152; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. | NEQ540; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. | 0.510 |
dnaG | NEQ208 | NEQ341 | NEQ208 | NEQ341; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | NEQ208; Arginyl-tRNA synthetase [Lactobacillus gasseri]; COG0018: Arginyl-tRNA synthetase; IPR002453: Beta tubulin; IPR001412: Aminoacyl-transfer RNA synthetases class-I; IPR001278: Arginyl-tRNA synthetase. | 0.728 |
dnaG | NEQ261 | NEQ341 | NEQ261 | NEQ341; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | NEQ261; Hypothetical protein; COG1676: tRNA splicing endonuclease; IPR002827: tRNA intron endonuclease. | 0.569 |
dnaG | endA | NEQ341 | NEQ205 | NEQ341; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | NEQ205; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp. | 0.662 |