STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NEQ230NEQ230; isoleucyl-tRNA synthetase [Pyrococcus furiosus]; COG0060: Isoleucyl-tRNA synthetase; IPR002300: t-RNA synthetase, class Ia; IPR002301: Isoleucyl-tRNA synthetase; IPR001412: Aminoacyl-transfer RNA synthetases class-I; Belongs to the class-I aminoacyl-tRNA synthetase family. (1016 aa)    
Predicted Functional Partners:
valS
NEQ252; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner (By similarity); Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
  
 
0.996
NEQ479
NEQ479; phenylalanyl-tRNA synthetase beta-chain [Pyrococcus furiosus]; COG0072: Phenylalanyl-tRNA synthetase beta subunit.
  
 
 0.987
leuS
NEQ239; Isoleucine tRNA synthetase [Methanococcus jannaschii]; COG0495: Leucyl-tRNA synthetase; COG0143: Methionyl-tRNA synthetase; IPR002300: t-RNA synthetase, class Ia; IPR002308: Cysteinyl-tRNA synthetase; IPR001412: Aminoacyl-transfer RNA synthetases class-I; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
0.984
NEQ208
NEQ208; Arginyl-tRNA synthetase [Lactobacillus gasseri]; COG0018: Arginyl-tRNA synthetase; IPR002453: Beta tubulin; IPR001412: Aminoacyl-transfer RNA synthetases class-I; IPR001278: Arginyl-tRNA synthetase.
  
 0.980
gltX
NEQ302; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
 
 0.959
metG
NEQ457; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
  
 0.959
NEQ417
NEQ417; Glycyl-tRNA synthetase [Pyrococcus abyssi]; COG0423: Glycyl-tRNA synthetase, class II; IPR002106: Aminoacyl-transfer RNA synthetases class-II; IPR002314: tRNA synthetases, class-II (G, H, P and S); IPR002315: Homodimeric glycyl-tRNA synthetase.
  
 
 0.928
aspS
NEQ535; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp).
  
 
 0.927
proS
NEQ210; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).
  
 0.923
tyrS
NEQ389; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 4 subfamily.
  
  
 0.905
Your Current Organism:
Nanoarchaeum equitans
NCBI taxonomy Id: 228908
Other names: Microarchaeum sp. Kin4-M, N. equitans Kin4-M, Nanoarchaeum equitans Kin4-M, Nanoarchaeum equitans str. Kin4-M
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.