STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
eif2bNEQ323; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family. (139 aa)    
Predicted Functional Partners:
NEQ270
NEQ270; Elongation factor Tu [Pyrococcus abyssi]; COG0050: GTPases - translation elongation factors; IPR000795: GTP-binding elongation factor; IPR001687: ATP/GTP-binding site motif A (P-loop).
   
 0.999
NEQ405
NEQ405; Translation initiation factor eIF2-alpha [Methanopyrus kandleri]; COG1093: Translation initiation factor eIF2alpha; IPR003029: S1 RNA binding domain.
   
 0.999
eif1a
NEQ130; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
 
 0.995
rps3
NEQ481; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family.
   
 0.987
rps17
NEQ326; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
 
  0.986
rps4e
NEQ478; Ribosomal protein S4 [Methanothermobacter thermautotrophicus]; COG1471: Ribosomal protein S4E; IPR000876: Ribosomal protein S4E; IPR002942: S4 domain.
  
  0.978
rps6e
NEQ105; Ribosomal protein S6E [Methanopyrus kandeleri]; COG2125: Ribosomal protein S6E (S10); IPR001377: Ribosomal protein S6e; IPR001472: Bipartite nuclear localization signal; Belongs to the eukaryotic ribosomal protein eS6 family.
   
 0.974
rps24e
NEQ548; SSU ribosomal protein S24E [Methanococcus jannashii]; COG2004: Ribosomal protein S24E; IPR001976: Ribosomal protein S24e; Belongs to the eukaryotic ribosomal protein eS24 family.
   
  0.971
rps3ae
NEQ375; Ribosomal protein S3AE [Methanopyrus kandleri]; COG1890: Ribosomal protein S3AE; IPR001593: Ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family.
  
  0.969
rps19
NEQ480; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
    
 0.968
Your Current Organism:
Nanoarchaeum equitans
NCBI taxonomy Id: 228908
Other names: Microarchaeum sp. Kin4-M, N. equitans Kin4-M, Nanoarchaeum equitans Kin4-M, Nanoarchaeum equitans str. Kin4-M
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