STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobBCobyrinic acid A,C-diamide synthase CobB; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (460 aa)    
Predicted Functional Partners:
cbiC
cobalt-precorrin-8X methylmutase CbiC.
 
 0.999
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
  
 0.997
cobD2
Putative threonine-phosphate decarboxylase CobD.
  
 0.983
cobD1
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
  
 0.979
cobT
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase CobT; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
  
 0.978
cbiT
cobalt-precorrin-6Y C(15)-methyltransferase; Decarboxylating.
  
 0.968
cbiL
Cobalt-precorrin-2 C(20)-methyltransferase CbiL; Belongs to the precorrin methyltransferase family.
  
 0.967
cbiJ
cobalt-precorrin-6A reductase CbiJ.
  
 0.966
cbiF
Cobalt-precorrin-4 C(11)-methyltransferase CbiF; Belongs to the precorrin methyltransferase family.
  
 0.965
cbiD
Putative cobalt-precorrin-6A synthase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
  
 0.955
Your Current Organism:
Thermoanaerobacter kivui
NCBI taxonomy Id: 2325
Other names: ATCC 33488, Acetogenium kivuense, Acetogenium kivui, DSM 2030, T. kivui, Thermoanaerobacter kivuense
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