node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ajs_1897 | Ajs_1898 | Ajs_1897 | Ajs_1898 | PFAM: protein of unknown function DUF853, NPT hydrolase putative; KEGG: pol:Bpro_1966 protein of unknown function DUF853, NPT hydrolase putative. | PFAM: protein of unknown function DUF28; KEGG: rfr:Rfer_2075 protein of unknown function DUF28. | 0.634 |
Ajs_1897 | hemF | Ajs_1897 | Ajs_1900 | PFAM: protein of unknown function DUF853, NPT hydrolase putative; KEGG: pol:Bpro_1966 protein of unknown function DUF853, NPT hydrolase putative. | Coproporphyrinogen oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | 0.547 |
Ajs_1897 | purD | Ajs_1897 | Ajs_1899 | PFAM: protein of unknown function DUF853, NPT hydrolase putative; KEGG: pol:Bpro_1966 protein of unknown function DUF853, NPT hydrolase putative. | KEGG: pol:Bpro_1969 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201; Belongs to the GARS family. | 0.592 |
Ajs_1898 | Ajs_1897 | Ajs_1898 | Ajs_1897 | PFAM: protein of unknown function DUF28; KEGG: rfr:Rfer_2075 protein of unknown function DUF28. | PFAM: protein of unknown function DUF853, NPT hydrolase putative; KEGG: pol:Bpro_1966 protein of unknown function DUF853, NPT hydrolase putative. | 0.634 |
Ajs_1898 | Ajs_1903 | Ajs_1898 | Ajs_1903 | PFAM: protein of unknown function DUF28; KEGG: rfr:Rfer_2075 protein of unknown function DUF28. | Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.641 |
Ajs_1898 | efp | Ajs_1898 | Ajs_2875 | PFAM: protein of unknown function DUF28; KEGG: rfr:Rfer_2075 protein of unknown function DUF28. | Translation elongation factor P (EF-P); Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | 0.680 |
Ajs_1898 | hemF | Ajs_1898 | Ajs_1900 | PFAM: protein of unknown function DUF28; KEGG: rfr:Rfer_2075 protein of unknown function DUF28. | Coproporphyrinogen oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | 0.823 |
Ajs_1898 | lepA | Ajs_1898 | Ajs_3270 | PFAM: protein of unknown function DUF28; KEGG: rfr:Rfer_2075 protein of unknown function DUF28. | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.629 |
Ajs_1898 | purD | Ajs_1898 | Ajs_1899 | PFAM: protein of unknown function DUF28; KEGG: rfr:Rfer_2075 protein of unknown function DUF28. | KEGG: pol:Bpro_1969 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201; Belongs to the GARS family. | 0.836 |
Ajs_1898 | rlmH | Ajs_1898 | Ajs_1902 | PFAM: protein of unknown function DUF28; KEGG: rfr:Rfer_2075 protein of unknown function DUF28. | Protein of unknown function DUF163; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.645 |
Ajs_1898 | rplS | Ajs_1898 | Ajs_3352 | PFAM: protein of unknown function DUF28; KEGG: rfr:Rfer_2075 protein of unknown function DUF28. | LSU ribosomal protein L19P; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. | 0.613 |
Ajs_1898 | rsfS | Ajs_1898 | Ajs_1901 | PFAM: protein of unknown function DUF28; KEGG: rfr:Rfer_2075 protein of unknown function DUF28. | Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.676 |
Ajs_1898 | tig | Ajs_1898 | Ajs_1208 | PFAM: protein of unknown function DUF28; KEGG: rfr:Rfer_2075 protein of unknown function DUF28. | Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. | 0.616 |
Ajs_1903 | Ajs_1898 | Ajs_1903 | Ajs_1898 | Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | PFAM: protein of unknown function DUF28; KEGG: rfr:Rfer_2075 protein of unknown function DUF28. | 0.641 |
Ajs_1903 | hemF | Ajs_1903 | Ajs_1900 | Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Coproporphyrinogen oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | 0.618 |
Ajs_1903 | purD | Ajs_1903 | Ajs_1899 | Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | KEGG: pol:Bpro_1969 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201; Belongs to the GARS family. | 0.668 |
Ajs_1903 | rlmH | Ajs_1903 | Ajs_1902 | Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Protein of unknown function DUF163; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.766 |
Ajs_1903 | rsfS | Ajs_1903 | Ajs_1901 | Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.761 |
efp | Ajs_1898 | Ajs_2875 | Ajs_1898 | Translation elongation factor P (EF-P); Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | PFAM: protein of unknown function DUF28; KEGG: rfr:Rfer_2075 protein of unknown function DUF28. | 0.680 |
efp | lepA | Ajs_2875 | Ajs_3270 | Translation elongation factor P (EF-P); Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.627 |