node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ajs_1001 | coaD | Ajs_1001 | Ajs_3516 | Phosphopantothenate-cysteine ligase / Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.955 |
Ajs_1001 | coaE | Ajs_1001 | Ajs_0802 | Phosphopantothenate-cysteine ligase / Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.594 |
Ajs_1001 | coaX | Ajs_1001 | Ajs_0534 | Phosphopantothenate-cysteine ligase / Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. | 0.943 |
Ajs_1001 | gmk | Ajs_1001 | Ajs_0947 | Phosphopantothenate-cysteine ligase / Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.496 |
Ajs_1001 | guaA | Ajs_1001 | Ajs_2547 | Phosphopantothenate-cysteine ligase / Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.425 |
Ajs_3104 | coaD | Ajs_3104 | Ajs_3516 | KEGG: csa:Csal_1723 diguanylate cyclase with PAS/PAC sensor; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.692 |
Ajs_3104 | coaE | Ajs_3104 | Ajs_0802 | KEGG: csa:Csal_1723 diguanylate cyclase with PAS/PAC sensor; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.623 |
Ajs_3104 | ftsY | Ajs_3104 | Ajs_3520 | KEGG: csa:Csal_1723 diguanylate cyclase with PAS/PAC sensor; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | 0.464 |
Ajs_3104 | gmk | Ajs_3104 | Ajs_0947 | KEGG: csa:Csal_1723 diguanylate cyclase with PAS/PAC sensor; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.472 |
Ajs_3104 | guaA | Ajs_3104 | Ajs_2547 | KEGG: csa:Csal_1723 diguanylate cyclase with PAS/PAC sensor; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.846 |
Ajs_3517 | Ajs_3518 | Ajs_3517 | Ajs_3518 | TIGRFAM: putative methyltransferase; PFAM: conserved hypothetical protein 95; KEGG: rfr:Rfer_1668 conserved hypothetical protein 95. | PFAM: peptidase M16 domain protein; KEGG: rfr:Rfer_1670 peptidase M16-like. | 0.864 |
Ajs_3517 | Ajs_3519 | Ajs_3517 | Ajs_3519 | TIGRFAM: putative methyltransferase; PFAM: conserved hypothetical protein 95; KEGG: rfr:Rfer_1668 conserved hypothetical protein 95. | PFAM: peptidase M16 domain protein; KEGG: rfr:Rfer_1671 peptidase M16-like; Belongs to the peptidase M16 family. | 0.855 |
Ajs_3517 | coaD | Ajs_3517 | Ajs_3516 | TIGRFAM: putative methyltransferase; PFAM: conserved hypothetical protein 95; KEGG: rfr:Rfer_1668 conserved hypothetical protein 95. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.952 |
Ajs_3517 | ftsY | Ajs_3517 | Ajs_3520 | TIGRFAM: putative methyltransferase; PFAM: conserved hypothetical protein 95; KEGG: rfr:Rfer_1668 conserved hypothetical protein 95. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | 0.836 |
Ajs_3518 | Ajs_3517 | Ajs_3518 | Ajs_3517 | PFAM: peptidase M16 domain protein; KEGG: rfr:Rfer_1670 peptidase M16-like. | TIGRFAM: putative methyltransferase; PFAM: conserved hypothetical protein 95; KEGG: rfr:Rfer_1668 conserved hypothetical protein 95. | 0.864 |
Ajs_3518 | Ajs_3519 | Ajs_3518 | Ajs_3519 | PFAM: peptidase M16 domain protein; KEGG: rfr:Rfer_1670 peptidase M16-like. | PFAM: peptidase M16 domain protein; KEGG: rfr:Rfer_1671 peptidase M16-like; Belongs to the peptidase M16 family. | 0.998 |
Ajs_3518 | coaD | Ajs_3518 | Ajs_3516 | PFAM: peptidase M16 domain protein; KEGG: rfr:Rfer_1670 peptidase M16-like. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.606 |
Ajs_3518 | ftsY | Ajs_3518 | Ajs_3520 | PFAM: peptidase M16 domain protein; KEGG: rfr:Rfer_1670 peptidase M16-like. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. | 0.697 |
Ajs_3519 | Ajs_3517 | Ajs_3519 | Ajs_3517 | PFAM: peptidase M16 domain protein; KEGG: rfr:Rfer_1671 peptidase M16-like; Belongs to the peptidase M16 family. | TIGRFAM: putative methyltransferase; PFAM: conserved hypothetical protein 95; KEGG: rfr:Rfer_1668 conserved hypothetical protein 95. | 0.855 |
Ajs_3519 | Ajs_3518 | Ajs_3519 | Ajs_3518 | PFAM: peptidase M16 domain protein; KEGG: rfr:Rfer_1671 peptidase M16-like; Belongs to the peptidase M16 family. | PFAM: peptidase M16 domain protein; KEGG: rfr:Rfer_1670 peptidase M16-like. | 0.998 |