node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ajs_2202 | Ajs_3598 | Ajs_2202 | Ajs_3598 | DNA mismatch repair enzyme (predicted ATPase)-like protein; KEGG: nma:NMA0428 hypothetical protein. | PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase; KEGG: bam:Bamb_3094 AAA ATPase, central domain protein. | 0.691 |
Ajs_2202 | Ajs_3931 | Ajs_2202 | Ajs_3931 | DNA mismatch repair enzyme (predicted ATPase)-like protein; KEGG: nma:NMA0428 hypothetical protein. | TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: pol:Bpro_4628 thioredoxin. | 0.404 |
Ajs_2202 | dnaJ | Ajs_2202 | Ajs_3219 | DNA mismatch repair enzyme (predicted ATPase)-like protein; KEGG: nma:NMA0428 hypothetical protein. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.873 |
Ajs_2202 | groL | Ajs_2202 | Ajs_0699 | DNA mismatch repair enzyme (predicted ATPase)-like protein; KEGG: nma:NMA0428 hypothetical protein. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.866 |
Ajs_2202 | groS | Ajs_2202 | Ajs_0700 | DNA mismatch repair enzyme (predicted ATPase)-like protein; KEGG: nma:NMA0428 hypothetical protein. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.779 |
Ajs_2202 | grpE | Ajs_2202 | Ajs_3217 | DNA mismatch repair enzyme (predicted ATPase)-like protein; KEGG: nma:NMA0428 hypothetical protein. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.752 |
Ajs_2202 | hslU | Ajs_2202 | Ajs_3680 | DNA mismatch repair enzyme (predicted ATPase)-like protein; KEGG: nma:NMA0428 hypothetical protein. | Heat shock protein HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.752 |
Ajs_2202 | hslV | Ajs_2202 | Ajs_3681 | DNA mismatch repair enzyme (predicted ATPase)-like protein; KEGG: nma:NMA0428 hypothetical protein. | HslV component of HslUV peptidase; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.761 |
Ajs_2202 | lon | Ajs_2202 | Ajs_1211 | DNA mismatch repair enzyme (predicted ATPase)-like protein; KEGG: nma:NMA0428 hypothetical protein. | ATP-dependent proteinase; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. | 0.588 |
Ajs_3598 | Ajs_2202 | Ajs_3598 | Ajs_2202 | PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase; KEGG: bam:Bamb_3094 AAA ATPase, central domain protein. | DNA mismatch repair enzyme (predicted ATPase)-like protein; KEGG: nma:NMA0428 hypothetical protein. | 0.691 |
Ajs_3598 | Ajs_3931 | Ajs_3598 | Ajs_3931 | PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase; KEGG: bam:Bamb_3094 AAA ATPase, central domain protein. | TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: pol:Bpro_4628 thioredoxin. | 0.463 |
Ajs_3598 | dnaJ | Ajs_3598 | Ajs_3219 | PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase; KEGG: bam:Bamb_3094 AAA ATPase, central domain protein. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.763 |
Ajs_3598 | groL | Ajs_3598 | Ajs_0699 | PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase; KEGG: bam:Bamb_3094 AAA ATPase, central domain protein. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.785 |
Ajs_3598 | groS | Ajs_3598 | Ajs_0700 | PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase; KEGG: bam:Bamb_3094 AAA ATPase, central domain protein. | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.460 |
Ajs_3598 | grpE | Ajs_3598 | Ajs_3217 | PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase; KEGG: bam:Bamb_3094 AAA ATPase, central domain protein. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.741 |
Ajs_3598 | hslU | Ajs_3598 | Ajs_3680 | PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase; KEGG: bam:Bamb_3094 AAA ATPase, central domain protein. | Heat shock protein HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. | 0.763 |
Ajs_3598 | hslV | Ajs_3598 | Ajs_3681 | PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase; KEGG: bam:Bamb_3094 AAA ATPase, central domain protein. | HslV component of HslUV peptidase; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. | 0.738 |
Ajs_3598 | htpG | Ajs_3598 | Ajs_0475 | PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase; KEGG: bam:Bamb_3094 AAA ATPase, central domain protein. | Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity. | 0.701 |
Ajs_3931 | Ajs_2202 | Ajs_3931 | Ajs_2202 | TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: pol:Bpro_4628 thioredoxin. | DNA mismatch repair enzyme (predicted ATPase)-like protein; KEGG: nma:NMA0428 hypothetical protein. | 0.404 |
Ajs_3931 | Ajs_3598 | Ajs_3931 | Ajs_3598 | TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: pol:Bpro_4628 thioredoxin. | PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase; KEGG: bam:Bamb_3094 AAA ATPase, central domain protein. | 0.463 |