node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HD_1003 | HD_1377 | HD_1003 | HD_1377 | Conserved hypothetical protein. | Conserved hypothetical protein; Belongs to the UPF0265 family. | 0.482 |
HD_1003 | HD_1495 | HD_1003 | HD_1495 | Conserved hypothetical protein. | Conserved hypothetical protein. | 0.734 |
HD_1003 | HD_1892 | HD_1003 | HD_1892 | Conserved hypothetical protein. | Conserved hypothetical protein. | 0.682 |
HD_1003 | hemX | HD_1003 | HD_1741 | Conserved hypothetical protein. | Putative uroporphyrinogen III C-methyltransferase. | 0.625 |
HD_1003 | lapA | HD_1003 | HD_1354 | Conserved hypothetical protein. | Conserved hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. | 0.719 |
HD_1003 | mukB | HD_1003 | HD_1582 | Conserved hypothetical protein. | Cell division protein MukB; Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division; Belongs to the SMC family. MukB subfamily. | 0.716 |
HD_1003 | mukE | HD_1003 | HD_1584 | Conserved hypothetical protein. | MukE protein; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF. | 0.723 |
HD_1003 | mukF | HD_1003 | HD_1585 | Conserved hypothetical protein. | MukF protein; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity. | 0.728 |
HD_1003 | uspA | HD_1003 | HD_1428 | Conserved hypothetical protein. | Universal stress protein A; Required for resistance to DNA-damaging agents. | 0.697 |
HD_1003 | zapB | HD_1003 | HD_1472 | Conserved hypothetical protein. | Conserved hypothetical protein; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA. | 0.611 |
HD_1377 | HD_1003 | HD_1377 | HD_1003 | Conserved hypothetical protein; Belongs to the UPF0265 family. | Conserved hypothetical protein. | 0.482 |
HD_1377 | HD_1495 | HD_1377 | HD_1495 | Conserved hypothetical protein; Belongs to the UPF0265 family. | Conserved hypothetical protein. | 0.707 |
HD_1377 | HD_1892 | HD_1377 | HD_1892 | Conserved hypothetical protein; Belongs to the UPF0265 family. | Conserved hypothetical protein. | 0.732 |
HD_1377 | lapA | HD_1377 | HD_1354 | Conserved hypothetical protein; Belongs to the UPF0265 family. | Conserved hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. | 0.751 |
HD_1377 | mukB | HD_1377 | HD_1582 | Conserved hypothetical protein; Belongs to the UPF0265 family. | Cell division protein MukB; Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division; Belongs to the SMC family. MukB subfamily. | 0.692 |
HD_1377 | mukE | HD_1377 | HD_1584 | Conserved hypothetical protein; Belongs to the UPF0265 family. | MukE protein; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF. | 0.716 |
HD_1377 | mukF | HD_1377 | HD_1585 | Conserved hypothetical protein; Belongs to the UPF0265 family. | MukF protein; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity. | 0.717 |
HD_1377 | uspA | HD_1377 | HD_1428 | Conserved hypothetical protein; Belongs to the UPF0265 family. | Universal stress protein A; Required for resistance to DNA-damaging agents. | 0.544 |
HD_1377 | zapB | HD_1377 | HD_1472 | Conserved hypothetical protein; Belongs to the UPF0265 family. | Conserved hypothetical protein; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA. | 0.775 |
HD_1495 | HD_1003 | HD_1495 | HD_1003 | Conserved hypothetical protein. | Conserved hypothetical protein. | 0.734 |