node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Acid_0438 | Acid_0439 | Acid_0438 | Acid_0439 | PFAM: cyclic nucleotide-binding; ATP-binding region, ATPase domain protein domain protein; KEGG: gvi:gll1662 similar to two-component sensor histidine kinase. | KEGG: nha:Nham_3998 putative DNA topoisomerase I. | 0.665 |
Acid_0439 | Acid_0438 | Acid_0439 | Acid_0438 | KEGG: nha:Nham_3998 putative DNA topoisomerase I. | PFAM: cyclic nucleotide-binding; ATP-binding region, ATPase domain protein domain protein; KEGG: gvi:gll1662 similar to two-component sensor histidine kinase. | 0.665 |
Acid_0439 | Acid_0740 | Acid_0439 | Acid_0740 | KEGG: nha:Nham_3998 putative DNA topoisomerase I. | ATP-dependent DNA helicase, RecQ family; KEGG: nfa:nfa2960 putative ATP-dependent DNA helicase; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like. | 0.808 |
Acid_0439 | Acid_0959 | Acid_0439 | Acid_0959 | KEGG: nha:Nham_3998 putative DNA topoisomerase I. | KEGG: aba:Acid345_3541 ATP-dependent DNA helicase, RecQ family; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like. | 0.808 |
Acid_0439 | Acid_2693 | Acid_0439 | Acid_2693 | KEGG: nha:Nham_3998 putative DNA topoisomerase I. | KEGG: bxe:Bxe_B1169 hypothetical protein. | 0.677 |
Acid_0439 | Acid_3033 | Acid_0439 | Acid_3033 | KEGG: nha:Nham_3998 putative DNA topoisomerase I. | PFAM: ATP dependent DNA ligase domain protein; ATP dependent DNA ligase; KEGG: sme:SMc03959 hypothetical protein. | 0.657 |
Acid_0439 | Acid_6821 | Acid_0439 | Acid_6821 | KEGG: nha:Nham_3998 putative DNA topoisomerase I. | PFAM: ATP dependent DNA ligase; KEGG: ret:RHE_PE00252 putative ATP-dependent DNA ligase protein. | 0.670 |
Acid_0439 | Acid_7732 | Acid_0439 | Acid_7732 | KEGG: nha:Nham_3998 putative DNA topoisomerase I. | DNA topoisomerase III; KEGG: cac:CAC3567 topoisomerase B; TIGRFAM: ATP-dependent DNA helicase, RecQ family; DNA topoisomerase III; PFAM: helicase domain protein; HRDC domain protein; TOPRIM domain protein; DEAD/DEAH box helicase domain protein; DNA topoisomerase, type IA, central domain protein; SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein; DEAD-like helicases-like. | 0.910 |
Acid_0439 | Acid_7844 | Acid_0439 | Acid_7844 | KEGG: nha:Nham_3998 putative DNA topoisomerase I. | PFAM: ATP dependent DNA ligase domain protein; ATP dependent DNA ligase; KEGG: pcu:pc1833 hypothetical protein. | 0.664 |
Acid_0439 | gyrB | Acid_0439 | Acid_0003 | KEGG: nha:Nham_3998 putative DNA topoisomerase I. | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.911 |
Acid_0439 | rnhB | Acid_0439 | Acid_2565 | KEGG: nha:Nham_3998 putative DNA topoisomerase I. | RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.846 |
Acid_0740 | Acid_0439 | Acid_0740 | Acid_0439 | ATP-dependent DNA helicase, RecQ family; KEGG: nfa:nfa2960 putative ATP-dependent DNA helicase; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like. | KEGG: nha:Nham_3998 putative DNA topoisomerase I. | 0.808 |
Acid_0740 | Acid_0959 | Acid_0740 | Acid_0959 | ATP-dependent DNA helicase, RecQ family; KEGG: nfa:nfa2960 putative ATP-dependent DNA helicase; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like. | KEGG: aba:Acid345_3541 ATP-dependent DNA helicase, RecQ family; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like. | 0.919 |
Acid_0740 | Acid_7732 | Acid_0740 | Acid_7732 | ATP-dependent DNA helicase, RecQ family; KEGG: nfa:nfa2960 putative ATP-dependent DNA helicase; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like. | DNA topoisomerase III; KEGG: cac:CAC3567 topoisomerase B; TIGRFAM: ATP-dependent DNA helicase, RecQ family; DNA topoisomerase III; PFAM: helicase domain protein; HRDC domain protein; TOPRIM domain protein; DEAD/DEAH box helicase domain protein; DNA topoisomerase, type IA, central domain protein; SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein; DEAD-like helicases-like. | 0.970 |
Acid_0740 | gyrB | Acid_0740 | Acid_0003 | ATP-dependent DNA helicase, RecQ family; KEGG: nfa:nfa2960 putative ATP-dependent DNA helicase; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like. | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.545 |
Acid_0740 | rnhB | Acid_0740 | Acid_2565 | ATP-dependent DNA helicase, RecQ family; KEGG: nfa:nfa2960 putative ATP-dependent DNA helicase; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like. | RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.603 |
Acid_0959 | Acid_0439 | Acid_0959 | Acid_0439 | KEGG: aba:Acid345_3541 ATP-dependent DNA helicase, RecQ family; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like. | KEGG: nha:Nham_3998 putative DNA topoisomerase I. | 0.808 |
Acid_0959 | Acid_0740 | Acid_0959 | Acid_0740 | KEGG: aba:Acid345_3541 ATP-dependent DNA helicase, RecQ family; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like. | ATP-dependent DNA helicase, RecQ family; KEGG: nfa:nfa2960 putative ATP-dependent DNA helicase; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like. | 0.919 |
Acid_0959 | Acid_7732 | Acid_0959 | Acid_7732 | KEGG: aba:Acid345_3541 ATP-dependent DNA helicase, RecQ family; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like. | DNA topoisomerase III; KEGG: cac:CAC3567 topoisomerase B; TIGRFAM: ATP-dependent DNA helicase, RecQ family; DNA topoisomerase III; PFAM: helicase domain protein; HRDC domain protein; TOPRIM domain protein; DEAD/DEAH box helicase domain protein; DNA topoisomerase, type IA, central domain protein; SMART: DNA topoisomerase I, ATP-binding; DNA topoisomerase I, DNA-binding; Toprim sub domain protein; DEAD-like helicases-like. | 0.972 |
Acid_0959 | gyrB | Acid_0959 | Acid_0003 | KEGG: aba:Acid345_3541 ATP-dependent DNA helicase, RecQ family; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like. | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.545 |