node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Acid_2760 | Acid_3463 | Acid_2760 | Acid_3463 | PFAM: 5'-3' exonuclease; SMART: Helix-hairpin-helix domain protein, class 2; KEGG: aba:Acid345_2424 5'-3' exonuclease. | DNA-(apurinic or apyrimidinic site) lyase / Formamidopyrimidine-DNA glycosylase; PFAM: Formamidopyrimidine-DNA glycolase; zinc finger, Fpg domain protein; KEGG: hch:HCH_02013 formamidopyrimidine-DNA glycosylase; Belongs to the FPG family. | 0.693 |
Acid_2760 | mutM | Acid_2760 | Acid_6700 | PFAM: 5'-3' exonuclease; SMART: Helix-hairpin-helix domain protein, class 2; KEGG: aba:Acid345_2424 5'-3' exonuclease. | DNA-(apurinic or apyrimidinic site) lyase / Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.602 |
Acid_2760 | polA | Acid_2760 | Acid_1347 | PFAM: 5'-3' exonuclease; SMART: Helix-hairpin-helix domain protein, class 2; KEGG: aba:Acid345_2424 5'-3' exonuclease. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.818 |
Acid_2845 | Acid_3463 | Acid_2845 | Acid_3463 | ATP dependent helicase, Lhr family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; DEAD/H associated domain protein; SMART: DEAD-like helicases-like; KEGG: aba:Acid345_0384 DEAD/DEAH box helicase-like. | DNA-(apurinic or apyrimidinic site) lyase / Formamidopyrimidine-DNA glycosylase; PFAM: Formamidopyrimidine-DNA glycolase; zinc finger, Fpg domain protein; KEGG: hch:HCH_02013 formamidopyrimidine-DNA glycosylase; Belongs to the FPG family. | 0.678 |
Acid_2845 | mutM | Acid_2845 | Acid_6700 | ATP dependent helicase, Lhr family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; DEAD/H associated domain protein; SMART: DEAD-like helicases-like; KEGG: aba:Acid345_0384 DEAD/DEAH box helicase-like. | DNA-(apurinic or apyrimidinic site) lyase / Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.539 |
Acid_3463 | Acid_2760 | Acid_3463 | Acid_2760 | DNA-(apurinic or apyrimidinic site) lyase / Formamidopyrimidine-DNA glycosylase; PFAM: Formamidopyrimidine-DNA glycolase; zinc finger, Fpg domain protein; KEGG: hch:HCH_02013 formamidopyrimidine-DNA glycosylase; Belongs to the FPG family. | PFAM: 5'-3' exonuclease; SMART: Helix-hairpin-helix domain protein, class 2; KEGG: aba:Acid345_2424 5'-3' exonuclease. | 0.693 |
Acid_3463 | Acid_2845 | Acid_3463 | Acid_2845 | DNA-(apurinic or apyrimidinic site) lyase / Formamidopyrimidine-DNA glycosylase; PFAM: Formamidopyrimidine-DNA glycolase; zinc finger, Fpg domain protein; KEGG: hch:HCH_02013 formamidopyrimidine-DNA glycosylase; Belongs to the FPG family. | ATP dependent helicase, Lhr family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; DEAD/H associated domain protein; SMART: DEAD-like helicases-like; KEGG: aba:Acid345_0384 DEAD/DEAH box helicase-like. | 0.678 |
Acid_3463 | Acid_5837 | Acid_3463 | Acid_5837 | DNA-(apurinic or apyrimidinic site) lyase / Formamidopyrimidine-DNA glycosylase; PFAM: Formamidopyrimidine-DNA glycolase; zinc finger, Fpg domain protein; KEGG: hch:HCH_02013 formamidopyrimidine-DNA glycosylase; Belongs to the FPG family. | ATP dependent helicase, Lhr family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; DEAD/H associated domain protein; SMART: DEAD-like helicases-like; KEGG: aba:Acid345_3770 DEAD/DEAH box helicase-like. | 0.539 |
Acid_3463 | coaE | Acid_3463 | Acid_4781 | DNA-(apurinic or apyrimidinic site) lyase / Formamidopyrimidine-DNA glycosylase; PFAM: Formamidopyrimidine-DNA glycolase; zinc finger, Fpg domain protein; KEGG: hch:HCH_02013 formamidopyrimidine-DNA glycosylase; Belongs to the FPG family. | Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.730 |
Acid_3463 | mutM | Acid_3463 | Acid_6700 | DNA-(apurinic or apyrimidinic site) lyase / Formamidopyrimidine-DNA glycosylase; PFAM: Formamidopyrimidine-DNA glycolase; zinc finger, Fpg domain protein; KEGG: hch:HCH_02013 formamidopyrimidine-DNA glycosylase; Belongs to the FPG family. | DNA-(apurinic or apyrimidinic site) lyase / Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.925 |
Acid_3463 | nth | Acid_3463 | Acid_3784 | DNA-(apurinic or apyrimidinic site) lyase / Formamidopyrimidine-DNA glycosylase; PFAM: Formamidopyrimidine-DNA glycolase; zinc finger, Fpg domain protein; KEGG: hch:HCH_02013 formamidopyrimidine-DNA glycosylase; Belongs to the FPG family. | DNA-(apurinic or apyrimidinic site) lyase / endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.646 |
Acid_3463 | polA | Acid_3463 | Acid_1347 | DNA-(apurinic or apyrimidinic site) lyase / Formamidopyrimidine-DNA glycosylase; PFAM: Formamidopyrimidine-DNA glycolase; zinc finger, Fpg domain protein; KEGG: hch:HCH_02013 formamidopyrimidine-DNA glycosylase; Belongs to the FPG family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.909 |
Acid_5837 | Acid_3463 | Acid_5837 | Acid_3463 | ATP dependent helicase, Lhr family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; DEAD/H associated domain protein; SMART: DEAD-like helicases-like; KEGG: aba:Acid345_3770 DEAD/DEAH box helicase-like. | DNA-(apurinic or apyrimidinic site) lyase / Formamidopyrimidine-DNA glycosylase; PFAM: Formamidopyrimidine-DNA glycolase; zinc finger, Fpg domain protein; KEGG: hch:HCH_02013 formamidopyrimidine-DNA glycosylase; Belongs to the FPG family. | 0.539 |
Acid_5837 | mutM | Acid_5837 | Acid_6700 | ATP dependent helicase, Lhr family; PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; DEAD/H associated domain protein; SMART: DEAD-like helicases-like; KEGG: aba:Acid345_3770 DEAD/DEAH box helicase-like. | DNA-(apurinic or apyrimidinic site) lyase / Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.539 |
Acid_6303 | mutM | Acid_6303 | Acid_6700 | Transcriptional regulator, XRE family; SMART: helix-turn-helix domain protein; KEGG: cvi:CV3539 hypothetical protein. | DNA-(apurinic or apyrimidinic site) lyase / Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.502 |
Acid_6698 | Acid_6699 | Acid_6698 | Acid_6699 | PFAM: nucleic acid binding, OB-fold, tRNA/helicase-type; KEGG: cyb:CYB_0768 lipoprotein, putative. | PFAM: Rieske [2Fe-2S] domain protein; KEGG: aba:Acid345_3347 Rieske (2Fe-2S) oxidoreductase. | 0.557 |
Acid_6698 | mutM | Acid_6698 | Acid_6700 | PFAM: nucleic acid binding, OB-fold, tRNA/helicase-type; KEGG: cyb:CYB_0768 lipoprotein, putative. | DNA-(apurinic or apyrimidinic site) lyase / Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.557 |
Acid_6699 | Acid_6698 | Acid_6699 | Acid_6698 | PFAM: Rieske [2Fe-2S] domain protein; KEGG: aba:Acid345_3347 Rieske (2Fe-2S) oxidoreductase. | PFAM: nucleic acid binding, OB-fold, tRNA/helicase-type; KEGG: cyb:CYB_0768 lipoprotein, putative. | 0.557 |
Acid_6699 | mutM | Acid_6699 | Acid_6700 | PFAM: Rieske [2Fe-2S] domain protein; KEGG: aba:Acid345_3347 Rieske (2Fe-2S) oxidoreductase. | DNA-(apurinic or apyrimidinic site) lyase / Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.775 |
coaE | Acid_3463 | Acid_4781 | Acid_3463 | Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | DNA-(apurinic or apyrimidinic site) lyase / Formamidopyrimidine-DNA glycosylase; PFAM: Formamidopyrimidine-DNA glycolase; zinc finger, Fpg domain protein; KEGG: hch:HCH_02013 formamidopyrimidine-DNA glycosylase; Belongs to the FPG family. | 0.730 |