node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Acid_0108 | Acid_0749 | Acid_0108 | Acid_0749 | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: gme:Gmet_2933 ThiS, thiamine-biosynthesis. | PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: aba:Acid345_2477 UBA/ThiF-type NAD/FAD binding protein. | 0.960 |
Acid_0108 | Acid_0755 | Acid_0108 | Acid_0755 | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: gme:Gmet_2933 ThiS, thiamine-biosynthesis. | PFAM: UBA/THIF-type NAD/FAD binding protein; Rhodanese domain protein; MoeZ/MoeB domain protein; KEGG: gvi:gll3412 molybdopterin biosynthesis MoeB protein homolog. | 0.970 |
Acid_0108 | Acid_1226 | Acid_0108 | Acid_1226 | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: gme:Gmet_2933 ThiS, thiamine-biosynthesis. | KEGG: ttj:TTHA0680 phosphomethylpyrimidine kinase (ThiD); TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | 0.853 |
Acid_0108 | Acid_5911 | Acid_0108 | Acid_5911 | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: gme:Gmet_2933 ThiS, thiamine-biosynthesis. | PFAM: molybdopterin biosynthesis MoaE; thiamineS protein; KEGG: aba:Acid345_2057 molybdopterin converting factor, subunit 1. | 0.439 |
Acid_0108 | mqnE | Acid_0108 | Acid_1309 | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: gme:Gmet_2933 ThiS, thiamine-biosynthesis. | Radical SAM domain protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. | 0.823 |
Acid_0108 | thiC | Acid_0108 | Acid_1400 | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: gme:Gmet_2933 ThiS, thiamine-biosynthesis. | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | 0.873 |
Acid_0108 | thiE | Acid_0108 | Acid_4942 | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: gme:Gmet_2933 ThiS, thiamine-biosynthesis. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.858 |
Acid_0108 | thiE-2 | Acid_0108 | Acid_6375 | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: gme:Gmet_2933 ThiS, thiamine-biosynthesis. | Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). | 0.858 |
Acid_0108 | thiG | Acid_0108 | Acid_7731 | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: gme:Gmet_2933 ThiS, thiamine-biosynthesis. | Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.992 |
Acid_0749 | Acid_0108 | Acid_0749 | Acid_0108 | PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: aba:Acid345_2477 UBA/ThiF-type NAD/FAD binding protein. | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: gme:Gmet_2933 ThiS, thiamine-biosynthesis. | 0.960 |
Acid_0749 | Acid_0755 | Acid_0749 | Acid_0755 | PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: aba:Acid345_2477 UBA/ThiF-type NAD/FAD binding protein. | PFAM: UBA/THIF-type NAD/FAD binding protein; Rhodanese domain protein; MoeZ/MoeB domain protein; KEGG: gvi:gll3412 molybdopterin biosynthesis MoeB protein homolog. | 0.931 |
Acid_0749 | Acid_1226 | Acid_0749 | Acid_1226 | PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: aba:Acid345_2477 UBA/ThiF-type NAD/FAD binding protein. | KEGG: ttj:TTHA0680 phosphomethylpyrimidine kinase (ThiD); TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | 0.746 |
Acid_0749 | Acid_5911 | Acid_0749 | Acid_5911 | PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: aba:Acid345_2477 UBA/ThiF-type NAD/FAD binding protein. | PFAM: molybdopterin biosynthesis MoaE; thiamineS protein; KEGG: aba:Acid345_2057 molybdopterin converting factor, subunit 1. | 0.999 |
Acid_0749 | mqnE | Acid_0749 | Acid_1309 | PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: aba:Acid345_2477 UBA/ThiF-type NAD/FAD binding protein. | Radical SAM domain protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. | 0.511 |
Acid_0749 | thiC | Acid_0749 | Acid_1400 | PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: aba:Acid345_2477 UBA/ThiF-type NAD/FAD binding protein. | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | 0.847 |
Acid_0749 | thiE | Acid_0749 | Acid_4942 | PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: aba:Acid345_2477 UBA/ThiF-type NAD/FAD binding protein. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.730 |
Acid_0749 | thiE-2 | Acid_0749 | Acid_6375 | PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: aba:Acid345_2477 UBA/ThiF-type NAD/FAD binding protein. | Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). | 0.719 |
Acid_0749 | thiG | Acid_0749 | Acid_7731 | PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: aba:Acid345_2477 UBA/ThiF-type NAD/FAD binding protein. | Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.943 |
Acid_0755 | Acid_0108 | Acid_0755 | Acid_0108 | PFAM: UBA/THIF-type NAD/FAD binding protein; Rhodanese domain protein; MoeZ/MoeB domain protein; KEGG: gvi:gll3412 molybdopterin biosynthesis MoeB protein homolog. | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: gme:Gmet_2933 ThiS, thiamine-biosynthesis. | 0.970 |
Acid_0755 | Acid_0749 | Acid_0755 | Acid_0749 | PFAM: UBA/THIF-type NAD/FAD binding protein; Rhodanese domain protein; MoeZ/MoeB domain protein; KEGG: gvi:gll3412 molybdopterin biosynthesis MoeB protein homolog. | PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: aba:Acid345_2477 UBA/ThiF-type NAD/FAD binding protein. | 0.931 |