node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cysE | hom | HH_1234 | HH_1750 | Serine acetyltransferase. | Homoserine dehydrogenase. | 0.815 |
cysE | metB | HH_1234 | HH_0062 | Serine acetyltransferase. | Cystathionine gamma-synthase. | 0.513 |
cysE | thrB | HH_1234 | HH_1013 | Serine acetyltransferase. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.827 |
hom | cysE | HH_1750 | HH_1234 | Homoserine dehydrogenase. | Serine acetyltransferase. | 0.815 |
hom | ilvE | HH_1750 | HH_0451 | Homoserine dehydrogenase. | Branched-chain-amino-acid aminotransferase IlvE; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.869 |
hom | metB | HH_1750 | HH_0062 | Homoserine dehydrogenase. | Cystathionine gamma-synthase. | 0.901 |
hom | metE | HH_1750 | HH_0852 | Homoserine dehydrogenase. | 5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.891 |
hom | metY | HH_1750 | HH_0636 | Homoserine dehydrogenase. | O-acetylhomoserine (thiol)-lyase MetY. | 0.855 |
hom | thrB | HH_1750 | HH_1013 | Homoserine dehydrogenase. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.993 |
hom | thrC | HH_1750 | HH_0527 | Homoserine dehydrogenase. | Threonine synthase. | 0.956 |
hom | ygaG | HH_1750 | HH_0176 | Homoserine dehydrogenase. | LuxS protein involved in autoinducer AI2 synthesis; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.811 |
ilvE | hom | HH_0451 | HH_1750 | Branched-chain-amino-acid aminotransferase IlvE; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | Homoserine dehydrogenase. | 0.869 |
ilvE | thrB | HH_0451 | HH_1013 | Branched-chain-amino-acid aminotransferase IlvE; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.829 |
infB | thrB | HH_1011 | HH_1013 | Translation initiation factor 2 (GTPase); One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.798 |
metB | cysE | HH_0062 | HH_1234 | Cystathionine gamma-synthase. | Serine acetyltransferase. | 0.513 |
metB | hom | HH_0062 | HH_1750 | Cystathionine gamma-synthase. | Homoserine dehydrogenase. | 0.901 |
metB | metE | HH_0062 | HH_0852 | Cystathionine gamma-synthase. | 5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.970 |
metB | metY | HH_0062 | HH_0636 | Cystathionine gamma-synthase. | O-acetylhomoserine (thiol)-lyase MetY. | 0.934 |
metB | thrB | HH_0062 | HH_1013 | Cystathionine gamma-synthase. | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.867 |
metB | ygaG | HH_0062 | HH_0176 | Cystathionine gamma-synthase. | LuxS protein involved in autoinducer AI2 synthesis; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. | 0.950 |