STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spoIIEStage II sporulation protein E (serine phosphatase). (826 aa)    
Predicted Functional Partners:
GK0058
Hypothetical conserved protein.
 
  
 0.950
GK0059
Serine/threonine protein kinase.
 
 
 0.934
spoIIGA
Protease (sporulation sigma-E factor processing peptidase); Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR.
  
  
 0.925
spoIIR
Stage II sporulation protein R (pro-sigma-E processing factor).
  
   
 0.825
spoIIP
Stage II sporulation protein P (septal wall dissolution protein).
  
   
 0.811
spoIIIAG
Stage III sporulation protein AG.
  
   
 0.800
GK3334
Transcriptional regulator of sigma-E/sigma-K-dependent gene (stage III sporulation protein D).
  
   
 0.784
spoIIM
Stage II sporulation protein M; Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane.
  
   
 0.782
spoIIIAE
Stage III sporulation protein AE.
  
     0.772
spoIIIAA
Stage III sporulation protein AA.
  
   
 0.769
Your Current Organism:
Geobacillus kaustophilus
NCBI taxonomy Id: 235909
Other names: G. kaustophilus HTA426, Geobacillus kaustophilus HTA426
Server load: low (38%) [HD]