STRINGSTRING
mcsB protein (Geobacillus kaustophilus) - STRING interaction network
"mcsB" - Protein-arginine kinase in Geobacillus kaustophilus
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mcsBProtein-arginine kinase; Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity (363 aa)    
Predicted Functional Partners:
GK0076
annotation not available (182 aa)
 
   
  0.999
hrcA
Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (344 aa)
     
   
  0.992
GK0075
annotation not available (153 aa)
 
     
  0.967
GK0078
annotation not available (810 aa)
   
 
  0.944
dnaK
Chaperone protein DnaK; Acts as a chaperone (607 aa)
     
 
  0.884
GK3373
annotation not available (148 aa)
   
   
  0.808
radA
DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3’ invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA’s homology-searching function (457 aa)
         
  0.755
groS
10 kDa chaperonin; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (93 aa)
     
 
  0.702
GK0080
annotation not available (364 aa)
 
          0.676
clpB
Chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family (862 aa)
   
 
  0.655
Your Current Organism:
Geobacillus kaustophilus
NCBI taxonomy Id: 235909
Other names: G. kaustophilus HTA426, Geobacillus kaustophilus, Geobacillus kaustophilus HTA426
Server load: low (15%) [HD]