node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
purC | purD | GK0260 | GK0268 | Phosphoribosylaminoimidazole succinocarboxamide synthetase; Belongs to the SAICAR synthetase family. | Phosphoribosylamine--glycine ligase; Phosphoribosylglycinamide synthetase (glycinamide ribonucleotide synthetase) (phosphoribosylglycinamide synthetase); Belongs to the GARS family. | 0.989 |
purC | purE | GK0260 | GK0257 | Phosphoribosylaminoimidazole succinocarboxamide synthetase; Belongs to the SAICAR synthetase family. | Phosphoribosylaminoimidazole carboxylasecatalytic chain; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.999 |
purC | purF | GK0260 | GK0264 | Phosphoribosylaminoimidazole succinocarboxamide synthetase; Belongs to the SAICAR synthetase family. | Phosphoribosylpyrophosphate amidotransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.996 |
purC | purH | GK0260 | GK0267 | Phosphoribosylaminoimidazole succinocarboxamide synthetase; Belongs to the SAICAR synthetase family. | Phosphoribosylaminoimidazolecarboxamide formyltransferase; IMP cyclohydrolase (bifunctional purine biosynthesis protein). | 0.990 |
purC | purK | GK0260 | GK0258 | Phosphoribosylaminoimidazole succinocarboxamide synthetase; Belongs to the SAICAR synthetase family. | Phosphoribosylaminoimidazole carboxylasecarbon dioxide-fixation chain; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.997 |
purC | purL | GK0260 | GK0263 | Phosphoribosylaminoimidazole succinocarboxamide synthetase; Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamidine (FGAM) synthasecomponent II (synthetase domain); Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with Pur [...] | 0.993 |
purC | purM | GK0260 | GK0265 | Phosphoribosylaminoimidazole succinocarboxamide synthetase; Belongs to the SAICAR synthetase family. | Phosphoribosylaminoimidazole synthetase (hosphoribosylformylglycinamidine cyclo-ligase). | 0.989 |
purC | purN | GK0260 | GK0266 | Phosphoribosylaminoimidazole succinocarboxamide synthetase; Belongs to the SAICAR synthetase family. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.985 |
purC | purQ | GK0260 | GK0262 | Phosphoribosylaminoimidazole succinocarboxamide synthetase; Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamidine (FGAM) synthasecomponent I (glutamine amidotransferase domain); Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS int [...] | 0.993 |
purC | purS | GK0260 | GK0261 | Phosphoribosylaminoimidazole succinocarboxamide synthetase; Belongs to the SAICAR synthetase family. | Phosphoribosylformylglycinamidine (FGAM) synthasePurS component; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is [...] | 0.991 |
purD | purC | GK0268 | GK0260 | Phosphoribosylamine--glycine ligase; Phosphoribosylglycinamide synthetase (glycinamide ribonucleotide synthetase) (phosphoribosylglycinamide synthetase); Belongs to the GARS family. | Phosphoribosylaminoimidazole succinocarboxamide synthetase; Belongs to the SAICAR synthetase family. | 0.989 |
purD | purE | GK0268 | GK0257 | Phosphoribosylamine--glycine ligase; Phosphoribosylglycinamide synthetase (glycinamide ribonucleotide synthetase) (phosphoribosylglycinamide synthetase); Belongs to the GARS family. | Phosphoribosylaminoimidazole carboxylasecatalytic chain; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.998 |
purD | purF | GK0268 | GK0264 | Phosphoribosylamine--glycine ligase; Phosphoribosylglycinamide synthetase (glycinamide ribonucleotide synthetase) (phosphoribosylglycinamide synthetase); Belongs to the GARS family. | Phosphoribosylpyrophosphate amidotransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.999 |
purD | purH | GK0268 | GK0267 | Phosphoribosylamine--glycine ligase; Phosphoribosylglycinamide synthetase (glycinamide ribonucleotide synthetase) (phosphoribosylglycinamide synthetase); Belongs to the GARS family. | Phosphoribosylaminoimidazolecarboxamide formyltransferase; IMP cyclohydrolase (bifunctional purine biosynthesis protein). | 0.996 |
purD | purK | GK0268 | GK0258 | Phosphoribosylamine--glycine ligase; Phosphoribosylglycinamide synthetase (glycinamide ribonucleotide synthetase) (phosphoribosylglycinamide synthetase); Belongs to the GARS family. | Phosphoribosylaminoimidazole carboxylasecarbon dioxide-fixation chain; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). | 0.993 |
purD | purL | GK0268 | GK0263 | Phosphoribosylamine--glycine ligase; Phosphoribosylglycinamide synthetase (glycinamide ribonucleotide synthetase) (phosphoribosylglycinamide synthetase); Belongs to the GARS family. | Phosphoribosylformylglycinamidine (FGAM) synthasecomponent II (synthetase domain); Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with Pur [...] | 0.993 |
purD | purM | GK0268 | GK0265 | Phosphoribosylamine--glycine ligase; Phosphoribosylglycinamide synthetase (glycinamide ribonucleotide synthetase) (phosphoribosylglycinamide synthetase); Belongs to the GARS family. | Phosphoribosylaminoimidazole synthetase (hosphoribosylformylglycinamidine cyclo-ligase). | 0.999 |
purD | purN | GK0268 | GK0266 | Phosphoribosylamine--glycine ligase; Phosphoribosylglycinamide synthetase (glycinamide ribonucleotide synthetase) (phosphoribosylglycinamide synthetase); Belongs to the GARS family. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.999 |
purD | purQ | GK0268 | GK0262 | Phosphoribosylamine--glycine ligase; Phosphoribosylglycinamide synthetase (glycinamide ribonucleotide synthetase) (phosphoribosylglycinamide synthetase); Belongs to the GARS family. | Phosphoribosylformylglycinamidine (FGAM) synthasecomponent I (glutamine amidotransferase domain); Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS int [...] | 0.999 |
purD | purS | GK0268 | GK0261 | Phosphoribosylamine--glycine ligase; Phosphoribosylglycinamide synthetase (glycinamide ribonucleotide synthetase) (phosphoribosylglycinamide synthetase); Belongs to the GARS family. | Phosphoribosylformylglycinamidine (FGAM) synthasePurS component; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is [...] | 0.990 |