STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemL1Glutamate-1-semialdehyde 2,1-aminomutase 2 (GSA). (428 aa)    
Predicted Functional Partners:
GK2643
Delta-aminolevulinic acid dehydratase (porphobilinogen synthase); Belongs to the ALAD family.
 
 
 0.990
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.985
hemC
Porphobilinogen deaminase (hydroxymethylbilane synthase); Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
  
 0.906
hemL2
Glutamate-1-semialdehyde 2,1-aminotransferase.
  
  
 
0.903
GK2644
Uroporphyrinogen III cosynthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
 
  
 0.759
GK0470
Hypothetical conserved protein.
       0.555
guaA
GMP synthetase (glutamine amidotransferase); Catalyzes the synthesis of GMP from XMP.
     
 0.534
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.530
GK1792
uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
 
   
 0.522
GK2297
Riboflavin-specific deaminase (diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.521
Your Current Organism:
Geobacillus kaustophilus
NCBI taxonomy Id: 235909
Other names: G. kaustophilus HTA426, Geobacillus kaustophilus HTA426
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