node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GK0712 | GK1060 | GK0712 | GK1060 | Pyruvate dehydrogenase E2 (dihydrolipoamide acetyltransferase). | Dihydrolipoamide acetyltransferase (E2 component of pyruvate dehydrogenase complex). | 0.908 |
GK0712 | GK1061 | GK0712 | GK1061 | Pyruvate dehydrogenase E2 (dihydrolipoamide acetyltransferase). | Dihydrolipoamide dehydrogenase (E3 component of pyruvate complex). | 0.996 |
GK0712 | GK2379 | GK0712 | GK2379 | Pyruvate dehydrogenase E2 (dihydrolipoamide acetyltransferase). | Branched-chain alpha-keto acid dehydrogenase E3 component (dihydrolipoamide dehydrogenase). | 0.995 |
GK0712 | GK3218 | GK0712 | GK3218 | Pyruvate dehydrogenase E2 (dihydrolipoamide acetyltransferase). | Pyruvate dehydrogenase E2 (dihydrolipoamide acetyltransferase). | 0.913 |
GK0712 | odhA | GK0712 | GK1023 | Pyruvate dehydrogenase E2 (dihydrolipoamide acetyltransferase). | 2-oxoglutarate dehydrogenase complex E1 component; E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). | 0.975 |
GK0712 | sucC | GK0712 | GK1208 | Pyruvate dehydrogenase E2 (dihydrolipoamide acetyltransferase). | succinyl-CoA synthetase beta subunit (succinate-CoA ligase beta subunit); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.947 |
GK0712 | sucD | GK0712 | GK1209 | Pyruvate dehydrogenase E2 (dihydrolipoamide acetyltransferase). | succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.937 |
GK1024 | GK1061 | GK1024 | GK1061 | 2-oxoglutarate dehydrogenase complex E2 component (dihydrolipoamide transsuccinylase); E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | Dihydrolipoamide dehydrogenase (E3 component of pyruvate complex). | 0.996 |
GK1024 | GK2379 | GK1024 | GK2379 | 2-oxoglutarate dehydrogenase complex E2 component (dihydrolipoamide transsuccinylase); E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | Branched-chain alpha-keto acid dehydrogenase E3 component (dihydrolipoamide dehydrogenase). | 0.996 |
GK1024 | odhA | GK1024 | GK1023 | 2-oxoglutarate dehydrogenase complex E2 component (dihydrolipoamide transsuccinylase); E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 2-oxoglutarate dehydrogenase complex E1 component; E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). | 0.999 |
GK1024 | sucC | GK1024 | GK1208 | 2-oxoglutarate dehydrogenase complex E2 component (dihydrolipoamide transsuccinylase); E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | succinyl-CoA synthetase beta subunit (succinate-CoA ligase beta subunit); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.976 |
GK1024 | sucD | GK1024 | GK1209 | 2-oxoglutarate dehydrogenase complex E2 component (dihydrolipoamide transsuccinylase); E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.974 |
GK1060 | GK0712 | GK1060 | GK0712 | Dihydrolipoamide acetyltransferase (E2 component of pyruvate dehydrogenase complex). | Pyruvate dehydrogenase E2 (dihydrolipoamide acetyltransferase). | 0.908 |
GK1060 | GK1061 | GK1060 | GK1061 | Dihydrolipoamide acetyltransferase (E2 component of pyruvate dehydrogenase complex). | Dihydrolipoamide dehydrogenase (E3 component of pyruvate complex). | 0.999 |
GK1060 | GK2379 | GK1060 | GK2379 | Dihydrolipoamide acetyltransferase (E2 component of pyruvate dehydrogenase complex). | Branched-chain alpha-keto acid dehydrogenase E3 component (dihydrolipoamide dehydrogenase). | 0.995 |
GK1060 | GK3218 | GK1060 | GK3218 | Dihydrolipoamide acetyltransferase (E2 component of pyruvate dehydrogenase complex). | Pyruvate dehydrogenase E2 (dihydrolipoamide acetyltransferase). | 0.909 |
GK1060 | odhA | GK1060 | GK1023 | Dihydrolipoamide acetyltransferase (E2 component of pyruvate dehydrogenase complex). | 2-oxoglutarate dehydrogenase complex E1 component; E1 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the decarboxylation of 2-oxoglutarate, the first step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2). | 0.978 |
GK1060 | sucC | GK1060 | GK1208 | Dihydrolipoamide acetyltransferase (E2 component of pyruvate dehydrogenase complex). | succinyl-CoA synthetase beta subunit (succinate-CoA ligase beta subunit); Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.940 |
GK1060 | sucD | GK1060 | GK1209 | Dihydrolipoamide acetyltransferase (E2 component of pyruvate dehydrogenase complex). | succinyl-CoA synthetase alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.937 |
GK1061 | GK0712 | GK1061 | GK0712 | Dihydrolipoamide dehydrogenase (E3 component of pyruvate complex). | Pyruvate dehydrogenase E2 (dihydrolipoamide acetyltransferase). | 0.996 |