node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GK0680 | GK1203 | GK0680 | GK1203 | Signal peptidase I (SPase I); Belongs to the peptidase S26 family. | Type I signal peptidase; Belongs to the peptidase S26 family. | 0.904 |
GK0680 | ftsZ | GK0680 | GK1125 | Signal peptidase I (SPase I); Belongs to the peptidase S26 family. | Cell-division initiation protein (septum formation); Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.488 |
GK0680 | rasP | GK0680 | GK1256 | Signal peptidase I (SPase I); Belongs to the peptidase S26 family. | Hypothetical conserved protein; Is responsible for Site-2 cleavage of the RsiW anti-sigma factor. This results, after a third proteolytic step catalyzed by the ClpXP protease, in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity). | 0.648 |
GK1203 | GK0680 | GK1203 | GK0680 | Type I signal peptidase; Belongs to the peptidase S26 family. | Signal peptidase I (SPase I); Belongs to the peptidase S26 family. | 0.904 |
GK1203 | frr | GK1203 | GK1252 | Type I signal peptidase; Belongs to the peptidase S26 family. | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.413 |
GK1203 | ftsZ | GK1203 | GK1125 | Type I signal peptidase; Belongs to the peptidase S26 family. | Cell-division initiation protein (septum formation); Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.431 |
GK1203 | rasP | GK1203 | GK1256 | Type I signal peptidase; Belongs to the peptidase S26 family. | Hypothetical conserved protein; Is responsible for Site-2 cleavage of the RsiW anti-sigma factor. This results, after a third proteolytic step catalyzed by the ClpXP protease, in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity). | 0.715 |
GK1203 | topA | GK1203 | GK1211 | Type I signal peptidase; Belongs to the peptidase S26 family. | DNA topoisomerase I (omega-protein) (relaxing enzyme) (untwisting enzyme); Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes pass [...] | 0.475 |
GK1254 | dxr | GK1254 | GK1255 | CDP-diglyceride synthase(phosphatidate cytidylyltransferase); Belongs to the CDS family. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXP reductoisomerase); Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | 0.927 |
GK1254 | frr | GK1254 | GK1252 | CDP-diglyceride synthase(phosphatidate cytidylyltransferase); Belongs to the CDS family. | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.749 |
GK1254 | ftsZ | GK1254 | GK1125 | CDP-diglyceride synthase(phosphatidate cytidylyltransferase); Belongs to the CDS family. | Cell-division initiation protein (septum formation); Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.427 |
GK1254 | proS | GK1254 | GK1257 | CDP-diglyceride synthase(phosphatidate cytidylyltransferase); Belongs to the CDS family. | proline-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves de [...] | 0.756 |
GK1254 | rasP | GK1254 | GK1256 | CDP-diglyceride synthase(phosphatidate cytidylyltransferase); Belongs to the CDS family. | Hypothetical conserved protein; Is responsible for Site-2 cleavage of the RsiW anti-sigma factor. This results, after a third proteolytic step catalyzed by the ClpXP protease, in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity). | 0.899 |
GK1254 | smbA | GK1254 | GK1251 | CDP-diglyceride synthase(phosphatidate cytidylyltransferase); Belongs to the CDS family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.781 |
GK1254 | uppS | GK1254 | GK1253 | CDP-diglyceride synthase(phosphatidate cytidylyltransferase); Belongs to the CDS family. | Undecaprenyl pyrophosphate synthetase (UPP synthetase); Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.976 |
dxr | GK1254 | GK1255 | GK1254 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXP reductoisomerase); Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | CDP-diglyceride synthase(phosphatidate cytidylyltransferase); Belongs to the CDS family. | 0.927 |
dxr | frr | GK1255 | GK1252 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXP reductoisomerase); Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. | 0.729 |
dxr | proS | GK1255 | GK1257 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXP reductoisomerase); Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | proline-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves de [...] | 0.845 |
dxr | rasP | GK1255 | GK1256 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXP reductoisomerase); Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Hypothetical conserved protein; Is responsible for Site-2 cleavage of the RsiW anti-sigma factor. This results, after a third proteolytic step catalyzed by the ClpXP protease, in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity). | 0.917 |
dxr | smbA | GK1255 | GK1251 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXP reductoisomerase); Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.670 |