STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proBGamma-glutamyl kinase (glutamate 5-kinase); Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (374 aa)    
Predicted Functional Partners:
proA
Gamma-glutamyl phosphate reductase (glutamate-5-semialdehyde dehydrogenase); Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
 
 0.999
rocD
Ornithine aminotransferase; Catalyzes the interconversion of ornithine to glutamate semialdehyde.
   
 0.929
rocA
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. RocA subfamily.
   
 
 0.904
GK2889
Pyrroline-5 carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 
 0.904
GK2047
Hypothetical protein.
       0.773
GK1431
Glutamate synthaselarge subunit.
 
  
 0.764
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
 
 
 0.729
guaA
GMP synthetase (glutamine amidotransferase); Catalyzes the synthesis of GMP from XMP.
  
 
 0.723
mscL
Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
     
 0.711
GK2964
Homoserine dehydrogenase.
 
  
 0.663
Your Current Organism:
Geobacillus kaustophilus
NCBI taxonomy Id: 235909
Other names: G. kaustophilus HTA426, Geobacillus kaustophilus HTA426
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