STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proAGamma-glutamyl phosphate reductase (glutamate-5-semialdehyde dehydrogenase); Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (414 aa)    
Predicted Functional Partners:
proB
Gamma-glutamyl kinase (glutamate 5-kinase); Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
 
 0.999
rocA
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. RocA subfamily.
   
 
 0.904
GK2889
Pyrroline-5 carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 
 0.904
GK1431
Glutamate synthaselarge subunit.
    
 0.892
purQ
Phosphoribosylformylglycinamidine (FGAM) synthasecomponent I (glutamine amidotransferase domain); Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS int [...]
  
 
 0.863
atpA
F0F1-type ATP synthasealpha chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.
 
    
 0.851
glnA
Glutamine synthetase (glutamate-ammonia ligase).
    
 0.838
GK1637
Glutamate-ammonia ligase; Belongs to the glutamine synthetase family.
    
 0.838
GK0189
NAD-specific glutamate dehydrogenase (NAD-GDH); Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
     
 0.820
GK2235
NAD-specific glutamate dehydrogenase (NAD-GDH); Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
     
 0.820
Your Current Organism:
Geobacillus kaustophilus
NCBI taxonomy Id: 235909
Other names: G. kaustophilus HTA426, Geobacillus kaustophilus HTA426
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