node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GK0684 | GK1295 | GK0684 | GK1295 | DNA exonuclease. | Hypothetical protein; Similar to N-terminal region of recombinase A (recA 345 aa) of Bacillus megaterium (GK1295 divided by group II intron (GK1296) is possibly continued to 1,316,291 bp). | 0.712 |
GK0684 | GK2104 | GK0684 | GK2104 | DNA exonuclease. | DNA/RNA helicase. | 0.553 |
GK0684 | dnaN | GK0684 | GK0002 | DNA exonuclease. | DNA-directed DNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for i [...] | 0.454 |
GK0684 | polA | GK0684 | GK2730 | DNA exonuclease. | DNA-directed DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.981 |
GK0684 | recQ | GK0684 | GK2243 | DNA exonuclease. | ATP-dependent DNA helicase. | 0.915 |
GK0684 | sbcD | GK0684 | GK0683 | DNA exonuclease. | DNA repair exonuclease; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | 0.999 |
GK1295 | GK0684 | GK1295 | GK0684 | Hypothetical protein; Similar to N-terminal region of recombinase A (recA 345 aa) of Bacillus megaterium (GK1295 divided by group II intron (GK1296) is possibly continued to 1,316,291 bp). | DNA exonuclease. | 0.712 |
GK1295 | GK1824 | GK1295 | GK1824 | Hypothetical protein; Similar to N-terminal region of recombinase A (recA 345 aa) of Bacillus megaterium (GK1295 divided by group II intron (GK1296) is possibly continued to 1,316,291 bp). | Hypothetical protein. | 0.422 |
GK1295 | dnaN | GK1295 | GK0002 | Hypothetical protein; Similar to N-terminal region of recombinase A (recA 345 aa) of Bacillus megaterium (GK1295 divided by group II intron (GK1296) is possibly continued to 1,316,291 bp). | DNA-directed DNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for i [...] | 0.929 |
GK1295 | mutL | GK1295 | GK1307 | Hypothetical protein; Similar to N-terminal region of recombinase A (recA 345 aa) of Bacillus megaterium (GK1295 divided by group II intron (GK1296) is possibly continued to 1,316,291 bp). | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.751 |
GK1295 | mutM | GK1295 | GK2728 | Hypothetical protein; Similar to N-terminal region of recombinase A (recA 345 aa) of Bacillus megaterium (GK1295 divided by group II intron (GK1296) is possibly continued to 1,316,291 bp). | formamidopyrimidine-DNA glycosidase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.518 |
GK1295 | mutS | GK1295 | GK1306 | Hypothetical protein; Similar to N-terminal region of recombinase A (recA 345 aa) of Bacillus megaterium (GK1295 divided by group II intron (GK1296) is possibly continued to 1,316,291 bp). | DNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.572 |
GK1295 | polA | GK1295 | GK2730 | Hypothetical protein; Similar to N-terminal region of recombinase A (recA 345 aa) of Bacillus megaterium (GK1295 divided by group II intron (GK1296) is possibly continued to 1,316,291 bp). | DNA-directed DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.992 |
GK1295 | recQ | GK1295 | GK2243 | Hypothetical protein; Similar to N-terminal region of recombinase A (recA 345 aa) of Bacillus megaterium (GK1295 divided by group II intron (GK1296) is possibly continued to 1,316,291 bp). | ATP-dependent DNA helicase. | 0.951 |
GK1295 | sbcD | GK1295 | GK0683 | Hypothetical protein; Similar to N-terminal region of recombinase A (recA 345 aa) of Bacillus megaterium (GK1295 divided by group II intron (GK1296) is possibly continued to 1,316,291 bp). | DNA repair exonuclease; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | 0.850 |
GK1824 | GK1295 | GK1824 | GK1295 | Hypothetical protein. | Hypothetical protein; Similar to N-terminal region of recombinase A (recA 345 aa) of Bacillus megaterium (GK1295 divided by group II intron (GK1296) is possibly continued to 1,316,291 bp). | 0.422 |
GK1824 | polA | GK1824 | GK2730 | Hypothetical protein. | DNA-directed DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.973 |
GK2104 | GK0684 | GK2104 | GK0684 | DNA/RNA helicase. | DNA exonuclease. | 0.553 |
GK2104 | dnaN | GK2104 | GK0002 | DNA/RNA helicase. | DNA-directed DNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for i [...] | 0.432 |
GK2104 | polA | GK2104 | GK2730 | DNA/RNA helicase. | DNA-directed DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.978 |