node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GK1292 | secA1 | GK1292 | GK3107 | Hypothetical conserved protein. | Preprotein translocase subunit (ATPase, RNA helicase); Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.674 |
GK1292 | secA2 | GK1292 | GK3170 | Hypothetical conserved protein. | Preprotein translocase subunit (ATPase, RNA helicase); Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.674 |
GK1295 | polA | GK1295 | GK2730 | Hypothetical protein; Similar to N-terminal region of recombinase A (recA 345 aa) of Bacillus megaterium (GK1295 divided by group II intron (GK1296) is possibly continued to 1,316,291 bp). | DNA-directed DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.992 |
GK1295 | prfB | GK1295 | GK3106 | Hypothetical protein; Similar to N-terminal region of recombinase A (recA 345 aa) of Bacillus megaterium (GK1295 divided by group II intron (GK1296) is possibly continued to 1,316,291 bp). | Peptide chain release factor 2 in translation; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | 0.509 |
GK1295 | secA1 | GK1295 | GK3107 | Hypothetical protein; Similar to N-terminal region of recombinase A (recA 345 aa) of Bacillus megaterium (GK1295 divided by group II intron (GK1296) is possibly continued to 1,316,291 bp). | Preprotein translocase subunit (ATPase, RNA helicase); Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.723 |
GK1295 | secA2 | GK1295 | GK3170 | Hypothetical protein; Similar to N-terminal region of recombinase A (recA 345 aa) of Bacillus megaterium (GK1295 divided by group II intron (GK1296) is possibly continued to 1,316,291 bp). | Preprotein translocase subunit (ATPase, RNA helicase); Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.742 |
GK1295 | secY | GK1295 | GK0126 | Hypothetical protein; Similar to N-terminal region of recombinase A (recA 345 aa) of Bacillus megaterium (GK1295 divided by group II intron (GK1296) is possibly continued to 1,316,291 bp). | Preprotein translocase subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.523 |
GK1295 | sigA | GK1295 | GK2482 | Hypothetical protein; Similar to N-terminal region of recombinase A (recA 345 aa) of Bacillus megaterium (GK1295 divided by group II intron (GK1296) is possibly continued to 1,316,291 bp). | DNA-directed RNA polymerase major sigma-43 factor (sigma-A); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.578 |
GK2701 | secA1 | GK2701 | GK3107 | Alkaline phosphatase; Belongs to the alkaline phosphatase family. | Preprotein translocase subunit (ATPase, RNA helicase); Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.693 |
GK2701 | secA2 | GK2701 | GK3170 | Alkaline phosphatase; Belongs to the alkaline phosphatase family. | Preprotein translocase subunit (ATPase, RNA helicase); Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.693 |
GK3046 | polA | GK3046 | GK2730 | Protein translocation subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | DNA-directed DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.544 |
GK3046 | secA1 | GK3046 | GK3107 | Protein translocation subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase subunit (ATPase, RNA helicase); Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.829 |
GK3046 | secA2 | GK3046 | GK3170 | Protein translocation subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase subunit (ATPase, RNA helicase); Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.829 |
GK3046 | secE | GK3046 | GK0091 | Protein translocation subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.979 |
GK3046 | secY | GK3046 | GK0126 | Protein translocation subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.947 |
polA | GK1295 | GK2730 | GK1295 | DNA-directed DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | Hypothetical protein; Similar to N-terminal region of recombinase A (recA 345 aa) of Bacillus megaterium (GK1295 divided by group II intron (GK1296) is possibly continued to 1,316,291 bp). | 0.992 |
polA | GK3046 | GK2730 | GK3046 | DNA-directed DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | Protein translocation subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.544 |
polA | secA1 | GK2730 | GK3107 | DNA-directed DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | Preprotein translocase subunit (ATPase, RNA helicase); Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.819 |
polA | secA2 | GK2730 | GK3170 | DNA-directed DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | Preprotein translocase subunit (ATPase, RNA helicase); Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.818 |
polA | secY | GK2730 | GK0126 | DNA-directed DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | Preprotein translocase subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.521 |