STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
icmFHypothetical conserved protein; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, and to a lesser extent, of pivalyl-CoA and isovaleryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. Also displays ATPase activity. Is not able to convert 3- hydroxybutyryl-CoA to 2-hydroxyisobutyryl-CoA. Does not exhibit methylmalonyl-CoA mutase (MCM) activity. (1086 aa)    
Predicted Functional Partners:
GK2370
methylmalonyl-CoA mutase large subunit.
 
 
0.998
GK2371
methylmalonyl-CoA mutase small subunit.
 
 
0.998
GK2369
Hypothetical conserved protein.
 
  
0.900
GK3392
Transcriptional regulator (TetR/AcrR family).
 
 
 
 0.888
GK2350
Lactoylglutathione lyase.
 
  
 0.846
GK3008
3-hydroxyacyl-CoA dehydrogenase.
 
  
 0.697
GK1301
2-oxoglutarate synthase(2-oxoglutarate-ferredoxin oxidoreductase) alpha subunit.
  
  
 0.632
GK3393
acyl-CoA dehydrogenase.
  
  
 0.604
GK2349
propionyl-CoA carboxylase.
 
  
 0.596
GK2948
ABC transporter (substrate-binding protein).
 
  
 0.584
Your Current Organism:
Geobacillus kaustophilus
NCBI taxonomy Id: 235909
Other names: G. kaustophilus HTA426, Geobacillus kaustophilus HTA426
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.