STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RBD2Rhomboid protein 2; Probable serine protease; Belongs to the peptidase S54 family. (284 aa)    
Predicted Functional Partners:
CaO19.1643
Rhomboid protease.
      
 0.940
CDC48
AAA family ATPase; Belongs to the AAA ATPase family.
    
 
 0.928
SPO1
Lysophospholipase.
      
 0.672
ECM14
Putative metallocarboxypeptidase.
   
  
 0.601
HMG1
3-hydroxy-3-methylglutaryl coenzyme A reductase.
   
  
 0.565
CaO19.6432
AAA family ATPase.
    
 
 0.555
ATP3
ATP synthase subunit gamma.
   
  
 0.479
CaO19.1595
UBX domain-containing protein.
    
 
 0.456
SEC11
Signal peptidase complex catalytic subunit SEC11; Catalytic component of the signal peptidase complex (SPC), which catalyzes the cleavage of N-terminal signal sequences of proteins targeted to the endoplasmic reticulum. Signal peptide cleavage occurs during the translocation (cotranslationally or post-translationally) through the translocon pore into the endoplasmic reticulum (By similarity).
      
 0.447
CaO19.2835
E1 ubiquitin-activating protein.
      
 0.445
Your Current Organism:
Candida albicans
NCBI taxonomy Id: 237561
Other names: C. albicans SC5314, Candida albicans SC5314
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.