hemL protein (Acidobacterium capsulatum) - STRING interaction network

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Score

hemL

Glutamate-1-semialdehyde-2,1-aminomutase; Identified by match to protein family HMM PF00202; match to protein family HMM TIGR00713. (429 aa)

Predicted Functional Partners:

hemB

0.989

hemA

0.985

hemC

0.883

ACP_3018

0.744

hemD

0.707

ACP_1162

0.696

cobA

0.643

ACP_1157

0.570

fabD

0.517

hemE

0.513

Your Current Organism:

Acidobacterium capsulatum

NCBI taxonomy Id: 240015
Other names: A. capsulatum ATCC 51196, Acidobacterium capsulatum ATCC 51196, Acidobacterium capsulatum str. ATCC 51196, Acidobacterium capsulatum strain ATCC 51196

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACP_1157	ACP_1162	ACP_1157	ACP_1162	Polyketide synthase peptide synthetase fusion protein; Identified by match to protein family HMM PF00109; match to protein family HMM PF00202; match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM TIGR01733.	Nonribosomal peptide synthetase; Identified by match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM PF00975; match to protein family HMM TIGR01733.	0.999
ACP_1157	fabD	ACP_1157	ACP_1923	Polyketide synthase peptide synthetase fusion protein; Identified by match to protein family HMM PF00109; match to protein family HMM PF00202; match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM TIGR01733.	Malonyl CoA-acyl carrier protein transacylase; Identified by similarity to SP:P71019; match to protein family HMM PF00698; match to protein family HMM TIGR00128.	0.734
ACP_1157	hemA	ACP_1157	ACP_0712	Polyketide synthase peptide synthetase fusion protein; Identified by match to protein family HMM PF00109; match to protein family HMM PF00202; match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM TIGR01733.	glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).	0.599
ACP_1157	hemB	ACP_1157	ACP_2188	Polyketide synthase peptide synthetase fusion protein; Identified by match to protein family HMM PF00109; match to protein family HMM PF00202; match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM TIGR01733.	Porphobilinogen synthase; Identified by match to protein family HMM PF00490; Belongs to the ALAD family.	0.649
ACP_1157	hemC	ACP_1157	ACP_0711	Polyketide synthase peptide synthetase fusion protein; Identified by match to protein family HMM PF00109; match to protein family HMM PF00202; match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM TIGR01733.	Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.	0.639
ACP_1157	hemD	ACP_1157	ACP_0710	Polyketide synthase peptide synthetase fusion protein; Identified by match to protein family HMM PF00109; match to protein family HMM PF00202; match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM TIGR01733.	uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.	0.413
ACP_1157	hemE	ACP_1157	ACP_2432	Polyketide synthase peptide synthetase fusion protein; Identified by match to protein family HMM PF00109; match to protein family HMM PF00202; match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM TIGR01733.	Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.	0.476
ACP_1157	hemL	ACP_1157	ACP_2074	Polyketide synthase peptide synthetase fusion protein; Identified by match to protein family HMM PF00109; match to protein family HMM PF00202; match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM TIGR01733.	Glutamate-1-semialdehyde-2,1-aminomutase; Identified by match to protein family HMM PF00202; match to protein family HMM TIGR00713.	0.570
ACP_1162	ACP_1157	ACP_1162	ACP_1157	Nonribosomal peptide synthetase; Identified by match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM PF00975; match to protein family HMM TIGR01733.	Polyketide synthase peptide synthetase fusion protein; Identified by match to protein family HMM PF00109; match to protein family HMM PF00202; match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM PF00698; match to protein family HMM PF02801; match to protein family HMM TIGR01733.	0.999
ACP_1162	fabD	ACP_1162	ACP_1923	Nonribosomal peptide synthetase; Identified by match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM PF00975; match to protein family HMM TIGR01733.	Malonyl CoA-acyl carrier protein transacylase; Identified by similarity to SP:P71019; match to protein family HMM PF00698; match to protein family HMM TIGR00128.	0.995
ACP_1162	hemL	ACP_1162	ACP_2074	Nonribosomal peptide synthetase; Identified by match to protein family HMM PF00501; match to protein family HMM PF00550; match to protein family HMM PF00668; match to protein family HMM PF00975; match to protein family HMM TIGR01733.	Glutamate-1-semialdehyde-2,1-aminomutase; Identified by match to protein family HMM PF00202; match to protein family HMM TIGR00713.	0.696
ACP_3018	cobA	ACP_3018	ACP_3338	Siroheme synthase, N-terminal domain protein; Identified by match to protein family HMM TIGR01470.	uroporphyrinogen-III C-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01469; Belongs to the precorrin methyltransferase family.	0.999
ACP_3018	hemA	ACP_3018	ACP_0712	Siroheme synthase, N-terminal domain protein; Identified by match to protein family HMM TIGR01470.	glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).	0.543
ACP_3018	hemB	ACP_3018	ACP_2188	Siroheme synthase, N-terminal domain protein; Identified by match to protein family HMM TIGR01470.	Porphobilinogen synthase; Identified by match to protein family HMM PF00490; Belongs to the ALAD family.	0.710
ACP_3018	hemC	ACP_3018	ACP_0711	Siroheme synthase, N-terminal domain protein; Identified by match to protein family HMM TIGR01470.	Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.	0.887
ACP_3018	hemD	ACP_3018	ACP_0710	Siroheme synthase, N-terminal domain protein; Identified by match to protein family HMM TIGR01470.	uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.	0.647
ACP_3018	hemL	ACP_3018	ACP_2074	Siroheme synthase, N-terminal domain protein; Identified by match to protein family HMM TIGR01470.	Glutamate-1-semialdehyde-2,1-aminomutase; Identified by match to protein family HMM PF00202; match to protein family HMM TIGR00713.	0.744
cobA	ACP_3018	ACP_3338	ACP_3018	uroporphyrinogen-III C-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01469; Belongs to the precorrin methyltransferase family.	Siroheme synthase, N-terminal domain protein; Identified by match to protein family HMM TIGR01470.	0.999
cobA	hemA	ACP_3338	ACP_0712	uroporphyrinogen-III C-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01469; Belongs to the precorrin methyltransferase family.	glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).	0.763
cobA	hemB	ACP_3338	ACP_2188	uroporphyrinogen-III C-methyltransferase; Identified by match to protein family HMM PF00590; match to protein family HMM TIGR01469; Belongs to the precorrin methyltransferase family.	Porphobilinogen synthase; Identified by match to protein family HMM PF00490; Belongs to the ALAD family.	0.884

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