STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepALeucyl aminopeptidase, Metallo peptidase, MEROPS family M17; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (491 aa)    
Predicted Functional Partners:
Ava_0316
Peptidase M1, membrane alanine aminopeptidase.
  
 0.935
Ava_3091
Gamma-glutamyltransferase 1, Threonine peptidase, MEROPS family T03.
     
 0.924
gshB
Glutathione synthase; Belongs to the prokaryotic GSH synthase family.
   
 
 0.915
Ava_4113
Enzymatic protein of unknown function; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
     
  0.900
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.843
Ava_0452
Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
 0.820
Ava_1347
Pyridoxal-5'-phosphate-dependent enzyme, beta subunit.
    
 0.820
Ava_2508
Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
 0.820
Ava_5019
Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
 0.820
Ava_2127
Aminotransferase.
   
  0.812
Your Current Organism:
Trichormus variabilis
NCBI taxonomy Id: 240292
Other names: Anabaena flos-aquae A-37, Anabaena flos-aquae UTCC 67, Anabaena sp. CCALA 007, Anabaena sp. PCC 7937, Anabaena variabilis ATCC 29413, Anabaena variabilis IAM M-204, Anabaena variabilis NIES-2095, Anabaena variabilis UTCC 105, Nostoc sp. PCC 7937, T. variabilis ATCC 29413, Trichormus variabilis ATCC 29413
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